Alnylam Pharmaceuticals, Inc.
ALNY Healthcare Biotechnology
Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024.
- Revenue
- +16.7%
- EPS
- +747.6%
- Free cash flow
- −4.76%
- Total debt
- −2.66%
Quarter to September 2026, against a year earlier
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Alnylam Pharmaceuticals, Inc. (ALNY) Return on invested capital
Alnylam Pharmaceuticals, Inc.'s return on invested capital over the twelve months to 30 September 2026 was 59.4%, up 59.4 percentage points from fiscal 2025 (0.00%). Over the past ten years it has ranged from −328.9% (fiscal 2019) to 0.00% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.
Return on invested capital, annual
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Annual newest first
| Period | Return on invested capital | Change (points) |
|---|---|---|
| FY2025 | 0.00% | 0.00 |
| FY2024 | 0.00% | 0.00 |
| FY2023 | 0.00% | 0.00 |
| FY2022 | 0.00% | 0.00 |
| FY2021 | 0.00% | 0.00 |
| FY2020 | 0.00% | 328.88 |
| FY2019 | −328.9% | (123.41) |
| FY2018 | −205.5% | 89.91 |
| FY2017 | −295.4% | (235.53) |
| FY2016 | −59.9% | 40.60 |
Against its own ten years
Return on invested capital against peers
| Company | Return on invested capital |
|---|---|
| EXEL Exelixis, Inc. compare | 66.6% |
| ALNY Alnylam Pharmaceuticals, Inc. | 59.4% |
| INCY Incyte Corporation compare | 21.6% |
| ASND Ascendis Pharma A/S compare | 15.1% |
| JAZZ Jazz Pharmaceuticals PLC compare | 3.86% |
| BBIO BridgeBio Pharma, Inc. compare | 0.00% |
| BNTX BioNTech SE Sponsored ADR compare | −34.3% |
| ROIV Roivant Sciences Ltd. compare | −34.5% |
| INSM Insmed, Inc. compare | −247.6% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Return on invested capital is
Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.
TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)
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- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
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- Operating margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
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- Current ratio
- Total debt
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