Ascendis Pharma A/S

ASND Healthcare Biotechnology

Ascendis Pharma A/S’s revenue for fiscal 2025 (year ended December 2025) was $814.8 million, up 107.1% from fiscal 2024.

Revenue
+119.9%
EPS
+612.3%
Free cash flow
+2,335.9%
Total debt
−41.8%

Quarter to June 2026, against a year earlier

256.11 2.66 +1.05%
Market cap
$16.6B
P/E
18.3×
Fwd P/E
15.4×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.51
Dividend safety
n/a

Ascendis Pharma A/S (ASND) Return on invested capital

Alert me on Return on invested capital

Ascendis Pharma A/S's return on invested capital over the twelve months to 30 June 2026 was 15.1%, up 106.7 percentage points from fiscal 2025 (−91.7%). Over the past ten years it has ranged from −84,748.4% (fiscal 2023) to 0.00% (fiscal 2017); the current reading is higher than 73% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 −91.7% (0.61)
FY2024 −91.0% 84,657.31
FY2023 −84,748.4% (83,780.24)
FY2022 −968.1% (874.66)
FY2021 −93.5% 1.35
FY2020 −94.8% 303.06
FY2019 −397.9% 4,022.81
FY2018 −4,420.7% (4,420.67)
FY2017 0.00% 0.00
FY2016 0.00% 3,844.07

Against its own ten years

Low −84,748.4% High 0.00%
Ten-year median −94.8%
Current reading's percentile 73

Return on invested capital against peers

Company Return on invested capital
EXEL Exelixis, Inc. compare 66.6%
ALNY Alnylam Pharmaceuticals, Inc. compare 59.4%
HALO Halozyme Therapeutics, Inc. compare 19.9%
ASND Ascendis Pharma A/S 15.1%
JAZZ Jazz Pharmaceuticals PLC compare 3.86%
BBIO BridgeBio Pharma, Inc. compare 0.00%
SMMT Summit Therapeutics PLC compare 0.00%
BNTX BioNTech SE Sponsored ADR compare −34.3%
INSM Insmed, Inc. compare −247.6%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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