Alnylam Pharmaceuticals, Inc.

ALNY Healthcare Biotechnology

Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024.

Revenue
+16.7%
EPS
+747.6%
Free cash flow
−4.76%
Total debt
−2.66%

Quarter to September 2026, against a year earlier

157.21 0.55 +0.35%
Market cap
$21.0B
P/E
7.9×
Fwd P/E
13.5×
Dividend yield
—
F-score
6/9
Altman Z
7.30
Beneish M
−1.95
Dividend safety
n/a

Alnylam Pharmaceuticals, Inc. (ALNY) Return on assets

Alert me on Return on assets

Alnylam Pharmaceuticals, Inc.'s return on assets over the twelve months to 30 September 2026 was 41.3%, up 34.4 percentage points from fiscal 2025 (6.82%). Over the past ten years it has ranged from −44.6% (fiscal 2019) to 6.82% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of −45.6% and above the Healthcare sector median of −29.3%.

Return on assets, annual

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Annual newest first

Period Return on assets Change (points)
FY2025 6.82% 13.71
FY2024 −6.89% 5.05
FY2023 −11.9% 19.53
FY2022 −31.5% (7.28)
FY2021 −24.2% 5.39
FY2020 −29.6% 15.06
FY2019 −44.6% (1.97)
FY2018 −42.7% (12.53)
FY2017 −30.1% 0.82
FY2016 −31.0% (7.44)

Against its own ten years

Low −44.6% High 6.82%
Ten-year median −29.6%
Current reading's percentile 100

Return on assets against peers

Company Return on assets
ASND Ascendis Pharma A/S compare 44.3%
ALNY Alnylam Pharmaceuticals, Inc. 41.3%
EXEL Exelixis, Inc. compare 33.2%
INCY Incyte Corporation compare 5.92%
JAZZ Jazz Pharmaceuticals PLC compare 1.76%
ROIV Roivant Sciences Ltd. compare −5.15%
BNTX BioNTech SE Sponsored ADR compare −7.22%
INSM Insmed, Inc. compare −26.4%
BBIO BridgeBio Pharma, Inc. compare −37.5%
Biotechnology industry median −45.6%
Healthcare sector median −29.3%
Market median 0.00%

What Return on assets is

ROA tells an investor how much profit a company earns for shareholders from the assets it uses to run its business.

Annual: Net Income Allotted to Shareholders ÷ Average Assets; TTM: Net Income Allotted to Shareholders ÷ Average Assets (latest quarter)

The full definition of Return on assets →

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