Alnylam Pharmaceuticals, Inc.

ALNY Healthcare Biotechnology

Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024. In the quarter to June 2026, revenue grew 66.9%, EPS grew 341.2%, free cash flow grew 152.8% and total debt fell 1.51%, each against the same quarter a year earlier. Member of the Nasdaq 100; revenue growth for five consecutive years.

231.83 2.20 −0.94%
Market cap
$31.3B
P/E
39.5×
Fwd P/E
39.6×
Dividend yield
—
F-score
6/9
Altman Z
7.30
Beneish M
−1.95
Dividend safety
n/a

Alnylam Pharmaceuticals, Inc. (ALNY) P/E ratio

Alert me on P/E ratio

As of 16 October 2026, Alnylam Pharmaceuticals, Inc. (ALNY) trades at a P/E ratio of 39.5×. Over the past ten years it has ranged from 0.0× (September 2025) to 806× (October 2025); the current reading is higher than 92% of that period. That is above the Biotechnology industry median of 8.5× and above the Healthcare sector median of 23.0×.

P/E ratio, daily

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Annual newest first

Period P/E ratio Change
FY2025 163× —
FY2024 0.0× —
FY2023 0.0× —
FY2022 0.0× —
FY2021 0.0× —
FY2020 0.0× —
FY2019 0.0× —
FY2018 0.0× —
FY2017 0.0× —
FY2016 0.0× —

Quarterly newest first

Period P/E ratio Change
Jun 2026 51.3× (35.99%)
Mar 2026 80.1× (50.87%)
Dec 2025 163× (78.20%)
Sep 2025 748× —
42 more quarters

Against its own ten years

Low 0.0× High 806×
Ten-year median 0.0×
Current reading's percentile 92

P/E ratio against peers

Company P/E ratio
ROIV Roivant Sciences Ltd. compare n/m
BNTX BioNTech SE Sponsored ADR compare n/m
RVMD Revolution Medicines, Inc. compare n/m
INSM Insmed, Inc. compare n/m
INCY Incyte Corporation compare 13.9×
GMAB Genmab A/S Sponsored ADR compare 29.1×
ALNY Alnylam Pharmaceuticals, Inc. 39.5×
RPRX Royalty Pharma PLC compare 42.3×
ONC BeOne Medicines Ltd. - Sponsored ADR compare 62.6×
Biotechnology industry median 8.5×
Healthcare sector median 23.0×
Market median 18.1×

What P/E ratio is

Price to Earnings Ratio shows how much investors pay for each dollar of a company’s annual profit per share.

Stock Price ÷ EPS (Basic) (TTM)

The full definition of P/E ratio →

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