Alnylam Pharmaceuticals, Inc.

ALNY Healthcare Biotechnology

Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024.

Revenue
+16.7%
EPS
+747.6%
Free cash flow
−4.76%
Total debt
−2.66%

Quarter to September 2026, against a year earlier

156.93 0.27 +0.17%
Market cap
$21.0B
P/E
7.9×
Fwd P/E
13.5×
Dividend yield
—
F-score
6/9
Altman Z
7.30
Beneish M
−1.95
Dividend safety
n/a

Alnylam Pharmaceuticals, Inc. (ALNY) P/E ratio

Alert me on P/E ratio

As of 5 November 2026, Alnylam Pharmaceuticals, Inc. (ALNY) trades at a P/E ratio of 7.9×. Over the past ten years it has ranged from 0.0× (September 2025) to 806× (October 2025); the current reading is higher than 91% of that period. That is below the Biotechnology industry median of 10.3× and below the Healthcare sector median of 25.2×.

P/E ratio, daily

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Annual newest first

Period P/E ratio Change
FY2025 189× —
FY2024 0.0× —
FY2023 0.0× —
FY2022 0.0× —
FY2021 0.0× —
FY2020 0.0× —
FY2019 0.0× —
FY2018 0.0× —
FY2017 0.0× —
FY2016 0.0× —

Quarterly newest first

Period P/E ratio Change
Sep 2026 12.5× (77.12%)
Jun 2026 54.4× (37.65%)
Mar 2026 87.3× (53.91%)
Dec 2025 189× (74.69%)
43 more quarters

Against its own ten years

Low 0.0× High 806×
Ten-year median 0.0×
Current reading's percentile 91

P/E ratio against peers

Company P/E ratio
ROIV Roivant Sciences Ltd. compare n/m
BNTX BioNTech SE Sponsored ADR compare n/m
BBIO BridgeBio Pharma, Inc. compare n/m
INSM Insmed, Inc. compare n/m
ALNY Alnylam Pharmaceuticals, Inc. 7.9×
ASND Ascendis Pharma A/S compare 18.3×
EXEL Exelixis, Inc. compare 19.9×
INCY Incyte Corporation compare 56.3×
JAZZ Jazz Pharmaceuticals PLC compare 62.6×
Biotechnology industry median 10.3×
Healthcare sector median 25.2×
Market median 17.9×

What P/E ratio is

Price to Earnings Ratio shows how much investors pay for each dollar of a company’s annual profit per share.

Stock Price ÷ EPS (Basic) (TTM)

The full definition of P/E ratio →

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