stockrowAlnylam Pharmaceuticals, Inc.
ALNY Healthcare Biotechnology
Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024.
- Revenue
- +16.7%
- EPS
- +747.6%
- Free cash flow
- −4.76%
- Total debt
- −2.66%
Quarter to September 2026, against a year earlier
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Alnylam Pharmaceuticals, Inc. (ALNY) Operating margin
Alnylam Pharmaceuticals, Inc.'s operating margin over the twelve months to 30 September 2026 was 19.5%, up 6.0 percentage points from fiscal 2025 (13.5%). Over the past ten years it has ranged from −1,087.6% (fiscal 2018) to 13.5% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.
Operating margin, annual
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Annual newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| FY2025 | 13.5% | 21.38 |
| FY2024 | −7.87% | 7.56 |
| FY2023 | −15.4% | 60.25 |
| FY2022 | −75.7% | 8.25 |
| FY2021 | −83.9% | 84.16 |
| FY2020 | −168.1% | 259.41 |
| FY2019 | −427.5% | 660.06 |
| FY2018 | −1,087.6% | (531.36) |
| FY2017 | −556.2% | 344.13 |
| FY2016 | −900.3% | (180.06) |
Quarterly newest first
| Period | Operating margin | Change (points) |
|---|---|---|
| Sep 2026 | 23.7% | 5.79 |
| Jun 2026 | 17.9% | (5.09) |
| Mar 2026 | 23.0% | 11.01 |
| Dec 2025 | 12.0% | (17.45) |
| 43 more quarters | Free account |
Against its own ten years
Operating margin against peers
| Company | Operating margin |
|---|---|
| EXEL Exelixis, Inc. compare | 40.2% |
| ASND Ascendis Pharma A/S compare | 24.8% |
| ALNY Alnylam Pharmaceuticals, Inc. | 19.5% |
| INCY Incyte Corporation compare | 10.4% |
| JAZZ Jazz Pharmaceuticals PLC compare | 9.03% |
| INSM Insmed, Inc. compare | −37.1% |
| BBIO BridgeBio Pharma, Inc. compare | −38.5% |
| BNTX BioNTech SE Sponsored ADR compare | −79.0% |
| ROIV Roivant Sciences Ltd. compare | −7,914.8% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Operating margin is
EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.
EBIT ÷ Revenue
More on ALNY
- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- Piotroski F-score
- Altman Z-score
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- The full statement