Alnylam Pharmaceuticals, Inc. (ALNY) vs Exelixis, Inc. (EXEL)

Alnylam Pharmaceuticals, Inc. and Exelixis, Inc. are both Biotechnology companies. Alnylam Pharmaceuticals, Inc. is the larger, with a market value of $21.0B against $16.8B — 1.3× the size. Alnylam Pharmaceuticals, Inc. trades at the lower P/E: 7.9× against 19.9×. Alnylam Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 56.2% against 9.12%. Alnylam Pharmaceuticals, Inc. has the higher net margin (52.9% vs 35.5%) and the lower return on invested capital (59.4% vs 66.6%). Across the 22 metrics below, Alnylam Pharmaceuticals, Inc. leads on 12 and Exelixis, Inc. on 10.

Valuation

Metric ALNY EXEL Biotechnology median
P/E 7.92 19.89 10.26
P/S 4.19 6.80 9.18
P/B 5.83 9.26 2.05
Price to free cash flow 26.05 14.84 24.81
EV/EBITDA 17.84 15.62 0.65
EV/Sales 3.68 6.45 8.98
Earnings yield 12.62% 5.03% (34.89%)
Free cash flow yield 3.84% 6.74% (24.52%)

Profitability

Metric ALNY EXEL Biotechnology median
Gross margin 77.28% 96.26% 65.16%
Operating margin 19.50% 40.19% 0.00%
Net margin 52.85% 35.45% 0.00%
Free cash flow margin 16.08% 45.84% 0.00%
Return on equity 138.07% 44.32% (50.12%)
Return on assets 41.25% 33.17% (45.60%)
Return on invested capital 59.37% 66.59% 0.00%

Growth

Metric ALNY EXEL Biotechnology median
Revenue growth (TTM) 56.17% 9.12% 6.26%
EPS growth (last fiscal year) 206.88% 57.95% 29.88%
Revenue growth, 5-year CAGR 49.77% 18.63% 9.75%
Net income growth, 5-year CAGR 0.00% 47.58% 0.00%

Health

Metric ALNY EXEL Biotechnology median
Debt to equity 0.28 0.00 0.00
Current ratio 2.48 3.21 4.89
Net debt to EBITDA (3.41) (1.18) 1.01

Dividend

Metric ALNY EXEL Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ALNY EXEL Biotechnology median
Market cap 20.98b 16.77b 172.11m

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