Alnylam Pharmaceuticals, Inc. (ALNY) vs BioNTech SE Sponsored ADR (BNTX)

Alnylam Pharmaceuticals, Inc. and BioNTech SE Sponsored ADR are both Biotechnology companies. Alnylam Pharmaceuticals, Inc. is the larger, with a market value of $31.2B against $24.9B — 1.2× the size. BioNTech SE Sponsored ADR has negative trailing earnings, so its P/E is not meaningful; Alnylam Pharmaceuticals, Inc. trades at 43.6×. Alnylam Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 95.1% against −3.33%. Alnylam Pharmaceuticals, Inc. has the higher net margin (16.1% vs −65.8%) and the higher return on invested capital (0.00% vs −38.4%). Both pay a dividend; Alnylam Pharmaceuticals, Inc. yields more (2.52% vs 1.33%). Across the 20 metrics below, Alnylam Pharmaceuticals, Inc. leads on 16 and BioNTech SE Sponsored ADR on 4.

Valuation

Metric ALNY BNTX Biotechnology median
P/E 43.62 n/m 7.88
P/S 7.12 8.27 11.47
P/B 25.25 1.21 2.52
Price to free cash flow 41.71 49.85 21.16
EV/EBITDA 30.25 n/m 0.74
EV/Sales 6.64 2.70 10.73
Earnings yield 2.29% (7.95%) (28.84%)
Free cash flow yield 2.40% 2.01% (23.03%)

Profitability

Metric ALNY BNTX Biotechnology median
Gross margin 79.65% 75.24% 65.16%
Operating margin 20.81% (77.94%) 0.00%
Net margin 16.13% (65.75%) 0.00%
Free cash flow margin 17.07% 16.58% 0.00%
Return on equity 96.55% (9.53%) (57.72%)
Return on assets 15.30% (8.24%) (49.22%)
Return on invested capital 0.00% (38.39%) 0.00%

Growth

Metric ALNY BNTX Biotechnology median
Revenue growth (TTM) 95.14% (3.33%) 5.64%
EPS growth (last fiscal year) 206.88% (77.33%) —
Revenue growth, 5-year CAGR 49.77% 42.58% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ALNY BNTX Biotechnology median
Debt to equity 0.75 0.02 0.00
Current ratio 3.05 7.85 4.73
Net debt to EBITDA (3.41) 14.29 0.96

Dividend

Metric ALNY BNTX Biotechnology median
Dividend yield 2.52% 1.33% 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric ALNY BNTX Biotechnology median
Market cap 31.16b 24.94b 162.10m

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