Alnylam Pharmaceuticals, Inc.

ALNY Healthcare Biotechnology

Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024.

Revenue
+16.7%
EPS
+747.6%
Free cash flow
−4.76%
Total debt
−2.66%

Quarter to September 2026, against a year earlier

157.21 0.55 +0.35%
Market cap
$21.0B
P/E
7.9×
Fwd P/E
13.5×
Dividend yield
—
F-score
6/9
Altman Z
7.30
Beneish M
−1.95
Dividend safety
n/a

Alnylam Pharmaceuticals, Inc. (ALNY) EBITDA

Alert me on EBITDA

Alnylam Pharmaceuticals, Inc.'s EBITDA for fiscal 2025 was $557.2M, compared with −$120.2M in fiscal 2024. Over the twelve months to 30 September 2026 it was $1.0B. Over the past ten years it has ranged from −$885.1M (fiscal 2019) to $557.2M (fiscal 2025) — the current reading is the highest in ten years. EBITDA has risen for 3 consecutive fiscal years. Alnylam Pharmaceuticals, Inc. ranks 8th of 594 Biotechnology companies by EBITDA.

EBITDA, annual

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Annual newest first

Period EBITDA Change
FY2025 $557.2M —
FY2024 −$120.2M —
FY2023 −$228.1M —
FY2022 −$740.6M —
FY2021 −$619.0M —
FY2020 −$754.0M —
FY2019 −$885.1M —
FY2018 −$799.4M —
FY2017 −$488.2M —
FY2016 −$409.5M —

Quarterly newest first

Period EBITDA Change
Sep 2026 $360.3M 46.85%
Jun 2026 $245.3M (13.06%)
Mar 2026 $282.2M 94.31%
Dec 2025 $145.2M (61.96%)
43 more quarters

Against its own ten years

Low −$885.1M High $557.2M
Ten-year median −$488.2M
Current reading's percentile 100

EBITDA against peers

What EBITDA is

EBITDA shows what a company earns from its operations before interest, taxes and the non-cash charges for depreciation and amortization.

Reported line item

The full definition of EBITDA →

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