Exelixis, Inc.

EXEL Healthcare Biotechnology

Exelixis, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $2.3 billion, up 6.98% from fiscal 2024.

Revenue
+10.2%
EPS
+22.2%
Free cash flow
−4.83%

Quarter to September 2026, against a year earlier

70.09 1.38 +2.01%
Market cap
$16.8B
P/E
19.9×
Fwd P/E
20.2×
Dividend yield
—
F-score
7/9
Altman Z
12.68
Beneish M
−2.61
Dividend safety
n/a

Exelixis, Inc. (EXEL) Return on invested capital

Alert me on Return on invested capital

Exelixis, Inc.'s return on invested capital over the twelve months to 30 September 2026 was 66.6%, up 17.1 percentage points from fiscal 2025 (49.5%). Over the past ten years it has ranged from −68.9% (fiscal 2015) to 49.5% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 49.5% 16.11
FY2024 33.4% 24.93
FY2023 8.42% (2.25)
FY2022 10.7% (13.43)
FY2021 24.1% 13.87
FY2020 10.2% (17.47)
FY2019 27.7% (18.47)
FY2018 46.2% 46.17
FY2017 0.00% 0.00
FY2016 0.00% 68.94

Against its own ten years

Low −68.9% High 49.5%
Ten-year median 10.7%
Current reading's percentile 100

Return on invested capital against peers

Company Return on invested capital
EXEL Exelixis, Inc. 66.6%
ALNY Alnylam Pharmaceuticals, Inc. compare 59.4%
HALO Halozyme Therapeutics, Inc. compare 19.9%
ASND Ascendis Pharma A/S compare 15.1%
JAZZ Jazz Pharmaceuticals PLC compare 3.86%
BBIO BridgeBio Pharma, Inc. compare 0.00%
SMMT Summit Therapeutics PLC compare 0.00%
BNTX BioNTech SE Sponsored ADR compare −34.3%
INSM Insmed, Inc. compare −247.6%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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