Alnylam Pharmaceuticals, Inc.

ALNY Healthcare Biotechnology

Alnylam Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.7 billion, up 65.2% from fiscal 2024.

Revenue
+16.7%
EPS
+747.6%
Free cash flow
−4.76%
Total debt
−2.66%

Quarter to September 2026, against a year earlier

156.74 0.08 +0.05%
Market cap
$21.0B
P/E
7.9×
Fwd P/E
13.5×
Dividend yield
—
F-score
6/9
Altman Z
7.30
Beneish M
−1.95
Dividend safety
n/a

Alnylam Pharmaceuticals, Inc. (ALNY) P/B ratio

Alert me on P/B ratio

As of 5 November 2026, Alnylam Pharmaceuticals, Inc. (ALNY) trades at a P/B ratio of 5.8×. Over the past ten years it has ranged from 0.0× (September 2024) to 1,195× (October 2024); the current reading is higher than 38% of that period. That is above the Biotechnology industry median of 2.0× and above the Healthcare sector median of 2.3×.

P/B ratio, daily

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Annual newest first

Period P/B ratio Change
FY2025 66.6× (85.12%)
FY2024 448× —
FY2023 0.0× —
FY2022 0.0× —
FY2021 34.1× 132.22%
FY2020 14.7× 68.13%
FY2019 8.7× 55.28%
FY2018 5.6× (16.66%)
FY2017 6.8× 88.06%
FY2016 3.6× (42.51%)

Quarterly newest first

Period P/B ratio Change
Sep 2026 9.2× (69.15%)
Jun 2026 29.7× (27.36%)
Mar 2026 40.9× (38.63%)
Dec 2025 66.6× (74.00%)
43 more quarters

Against its own ten years

Low 0.0× High 1,195×
Ten-year median 6.8×
Current reading's percentile 26

P/B ratio against peers

Company P/B ratio
BBIO BridgeBio Pharma, Inc. compare n/m
BNTX BioNTech SE Sponsored ADR compare 1.1×
JAZZ Jazz Pharmaceuticals PLC compare 3.5×
INCY Incyte Corporation compare 4.3×
ROIV Roivant Sciences Ltd. compare 5.4×
ALNY Alnylam Pharmaceuticals, Inc. 5.8×
EXEL Exelixis, Inc. compare 9.3×
ASND Ascendis Pharma A/S compare 9.8×
INSM Insmed, Inc. compare 32.6×
Biotechnology industry median 2.0×
Healthcare sector median 2.3×
Market median 1.7×

What P/B ratio is

Price to Book Value tells an investor how much the market pays for a company’s shares relative to the accounting net worth that belongs to common shareholders.

Stock Price ÷ (Common Equity (Total) (latest quarter) ÷ Shares (Basic, Weighted) (latest quarter))

The full definition of P/B ratio →

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