Friday 6 November 2026 Export KRYS’s income statement to Excel — free account

Krystal Biotech, Inc.

Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024.

Revenue: +30.2%
EPS: −22.3%
Free cash flow: +137.8%

Quarter to September 2026, against a year earlier

Operating cash flow growth 3 yrs

300.31 0.06 +0.02%

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Market cap: $8.9B
P/E: 39.2×
Fwd P/E: 45.7×
Dividend yield: —
F-score: 7/9
Altman Z: 39.03
Beneish M: −2.27
Dividend safety: n/a

Overview Business Profile Earnings & Analysis Valuation Filings

Krystal Biotech, Inc. (KRYS) P/E ratio

Alert me on P/E ratio

As of 6 November 2026, Krystal Biotech, Inc. (KRYS) trades at a P/E ratio of 39.2×. Over the past ten years it has ranged from 0.0× (December 2023) to 996× (March 2024); the current reading is higher than 81% of that period. That is above the Biotechnology industry median of 10.6× and above the Healthcare sector median of 24.5×.

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<iframe src="https://stockrow.com/embed/KRYS/pe-ratio" width="100%" height="360" style="border:0" loading="lazy" title="Krystal Biotech, Inc. P/E ratio, 10 years"></iframe>
<p style="font-size:12px">Source: <a href="https://stockrow.com/KRYS/metrics/pe-ratio">Krystal Biotech, Inc. (KRYS) P/E ratio — stockrow.com</a></p>

Period	P/E ratio	Change
FY2025	34.8×	(31.09%)
FY2024	50.5×	(92.72%)
FY2023	694×	—

Period	P/E ratio	Change
Sep 2026	43.4×	(3.40%)
Jun 2026	44.9×	34.83%
Mar 2026	33.3×	(4.28%)
Dec 2025	34.8×	35.91%
9 more quarters	Free account

Against its own ten years

Low 0.0× High 996×

Ten-year median 0.0×

Current reading's percentile 81

Company	P/E ratio
TWST Twist Bioscience Corporation compare	n/m
SYRE Spyre Therapeutics, Inc. compare	n/m
IBRX ImmunityBio, Inc. compare	n/m
MDGL Madrigal Pharmaceuticals, Inc. compare	n/m
ARWR Arrowhead Pharmaceuticals, Inc. compare	n/m
PCVX Vaxcyte, Inc. compare	n/m
TGTX TG Therapeutics, Inc. compare	19.6×
KRYS Krystal Biotech, Inc.	39.2×
PTGX Protagonist Therapeutics, Inc. compare	108×
Biotechnology industry median	10.6×
Healthcare sector median	24.5×
Market median	17.8×

What P/E ratio is

Price to Earnings Ratio shows how much investors pay for each dollar of a company’s annual profit per share.

Stock Price ÷ EPS (Basic) (TTM)

The full definition of P/E ratio →

Krystal Biotech, Inc. (KRYS) P/E ratio

P/E ratio, daily

Annual newest first

Quarterly newest first

Against its own ten years

P/E ratio against peers

What P/E ratio is

More on KRYS

P/E ratio, daily

Annual newest first

Quarterly newest first

Against its own ten years

P/E ratio against peers

What P/E ratio is

More on KRYS

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