Krystal Biotech, Inc.

KRYS Healthcare Biotechnology

Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024.

Revenue
+30.2%
EPS
−22.3%
Free cash flow
+137.8%

Quarter to September 2026, against a year earlier

300.31 0.06 +0.02%
Market cap
$8.9B
P/E
39.2×
Fwd P/E
45.7×
Dividend yield
—
F-score
7/9
Altman Z
39.03
Beneish M
−2.27
Dividend safety
n/a

Krystal Biotech, Inc. (KRYS) Return on assets

Alert me on Return on assets

Krystal Biotech, Inc.'s return on assets over the twelve months to 30 September 2026 was 15.9%, down 1.2 percentage points from fiscal 2025 (17.1%). Over the past ten years it has ranged from −30.3% (fiscal 2017) to 17.1% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of −45.6% and above the Healthcare sector median of −29.3%.

Return on assets, annual

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Annual newest first

Period Return on assets Change (points)
FY2025 17.1% 7.63
FY2024 9.51% 7.92
FY2023 1.59% 25.22
FY2022 −23.6% (8.78)
FY2021 −14.9% (2.47)
FY2020 −12.4% (0.64)
FY2019 −11.7% 1.36
FY2018 −13.1% 17.19
FY2017 −30.3% (25.89)
FY2016 −4.40% —

Against its own ten years

Low −30.3% High 17.1%
Ten-year median −12.1%
Current reading's percentile 100

Return on assets against peers

Company Return on assets
TGTX TG Therapeutics, Inc. compare 37.7%
KRYS Krystal Biotech, Inc. 15.9%
PTGX Protagonist Therapeutics, Inc. compare 10.3%
CAI Caris Life Sciences,�Inc. compare 8.58%
MDGL Madrigal Pharmaceuticals, Inc. compare −11.1%
TWST Twist Bioscience Corporation compare −20.8%
SYRE Spyre Therapeutics, Inc. compare −30.9%
CYTK Cytokinetics, Incorporated compare −47.7%
IBRX ImmunityBio, Inc. compare −192.6%
Biotechnology industry median −45.6%
Healthcare sector median −29.3%
Market median 0.00%

What Return on assets is

ROA tells an investor how much profit a company earns for shareholders from the assets it uses to run its business.

Annual: Net Income Allotted to Shareholders ÷ Average Assets; TTM: Net Income Allotted to Shareholders ÷ Average Assets (latest quarter)

The full definition of Return on assets →

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