Krystal Biotech, Inc.

KRYS Healthcare Biotechnology

Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024.

Revenue
+30.2%
EPS
−22.3%
Free cash flow
+137.8%

Quarter to September 2026, against a year earlier

303.69 3.44 +1.15%
Market cap
$8.9B
P/E
39.2×
Fwd P/E
45.7×
Dividend yield
—
F-score
7/9
Altman Z
39.03
Beneish M
−2.27
Dividend safety
n/a

Krystal Biotech, Inc. (KRYS) Free cash flow margin

Alert me on Free cash flow margin

Krystal Biotech, Inc.'s free cash flow margin over the twelve months to 30 September 2026 was 66.0%, up 17.3 percentage points from fiscal 2025 (48.7%). Over the past ten years it has ranged from −1.19% (fiscal 2023) to 48.7% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Free cash flow margin, annual

Embed this chart

Annual newest first

Period Free cash flow margin Change (points)
FY2025 48.7% 7.64
FY2024 41.0% 42.21
FY2023 −1.19% (1.19)
FY2022 0.00% 0.00
FY2021 0.00% 0.00
FY2020 0.00% 0.00
FY2019 0.00% 0.00
FY2018 0.00% 0.00
FY2017 0.00% 0.00
FY2016 0.00% —

Against its own ten years

Low −1.19% High 48.7%
Ten-year median 0.00%
Current reading's percentile 100

Free cash flow margin against peers

Company Free cash flow margin
KRYS Krystal Biotech, Inc. 66.0%
PTGX Protagonist Therapeutics, Inc. compare 46.3%
CAI Caris Life Sciences,�Inc. compare 8.00%
TGTX TG Therapeutics, Inc. compare 2.17%
SYRE Spyre Therapeutics, Inc. compare 0.00%
MDGL Madrigal Pharmaceuticals, Inc. compare −11.8%
TWST Twist Bioscience Corporation compare −22.2%
IBRX ImmunityBio, Inc. compare −173.8%
CYTK Cytokinetics, Incorporated compare −519.5%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Free cash flow margin is

Free Cash Flow Margin tells an investor how much of each sale turns into cash the company keeps after paying for investment in its assets.

(Operating Cash Flow + Property, Plant, Equipment Change (Net) + Intangible Assets Change (Net)) ÷ Revenue

The full definition of Free cash flow margin →

More on KRYS