stockrowKrystal Biotech, Inc. (KRYS) vs Spyre Therapeutics, Inc. (SYRE)
- Krystal Biotech, Inc. KRYS 303.69 +1.15%
- Spyre Therapeutics, Inc. SYRE 101.85 +5.45%
Krystal Biotech, Inc. and Spyre Therapeutics, Inc. are both Biotechnology companies. Krystal Biotech, Inc. and Spyre Therapeutics, Inc. are of similar size ($9.2B and $8.9B). Spyre Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Krystal Biotech, Inc. trades at 39.2×. Krystal Biotech, Inc. grew revenue faster over the last twelve months: 26.0% against −81.8%. Krystal Biotech, Inc. has the higher net margin (47.9% vs 0.00%) and the higher return on invested capital (27.2% vs 0.00%). Across the 16 metrics below, Krystal Biotech, Inc. leads on 14 and Spyre Therapeutics, Inc. on 2.
Valuation
Profitability
| Metric | KRYS | SYRE | Biotechnology median |
|---|---|---|---|
| Gross margin | 94.27% | 100.00% | 65.16% |
| Operating margin | 48.41% | 0.00% | 0.00% |
| Net margin | 47.91% | 0.00% | 0.00% |
| Free cash flow margin | 65.97% | 0.00% | 0.00% |
| Return on equity | 17.50% | (41.15%) | (50.12%) |
| Return on assets | 15.93% | (30.89%) | (45.60%) |
| Return on invested capital | 27.15% | 0.00% | 0.00% |
Growth
Health
Dividend
Size
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