Saturday 17 October 2026
Export KRYS’s income statement to Excel — free account
Krystal Biotech, Inc.
KRYS Healthcare Biotechnology
Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024. In the quarter to June 2026, revenue grew 24.1%, EPS grew 39.1% and free cash flow grew 40.1%, each against the same quarter a year earlier. Operating cash flow growth for three consecutive years.
316.58
13.42
−4.07%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | 8.03 | 8.61 | 18.50 | 33.09 | 38.86 | 47.67 | 69.81 | 107.50 | 122.80 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | 11.98 | 28.75 | 66.50 | 66.85 | 102.99 | 85.11 | 132.68 | 219.34 | 265.92 | |||||
| People | |||||||||||||||
| People | Employees | 7 | 12 | 37 | 53 | 75 | 119 | 210 | 229 | 275 | 295 | ||||
| Revenue/emp, $m | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 1.06 | 1.32 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | — | — | — | — | 51 | 291 | 389 | ||||
| Gross margin, % | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 93.90 | 93.09 | 94.08 | |||||
| EBT | (1) | (8) | (11) | (19) | (32) | (70) | (140) | 13 | 95 | 189 | |||||
| EBT margin, % | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 25.44 | 32.82 | 48.69 | |||||
| Net income | (1) | (8) | (11) | (19) | (32) | (70) | (140) | 11 | 89 | 205 | |||||
| Depreciation | 0 | 0 | 0 | 1 | 2 | 3 | 3 | 6 | 7 | 7 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.87 | 10.16 | 13.44 | ||||
| Earnings | (1.31) | (1.48) | (0.97) | (1.20) | (1.71) | (3.13) | (5.49) | 0.40 | 3.12 | 7.08 | |||||
| Cash flow | (1.49) | (0.73) | (0.84) | (1.18) | (1.39) | (2.16) | (3.95) | (3.27) | 4.32 | 6.94 | |||||
| Capex | (0.02) | (0.04) | (0.20) | (0.40) | (0.79) | (3.08) | (2.08) | 3.25 | (0.15) | (0.40) | |||||
| Free cash flow | (1.51) | (0.76) | (1.04) | (1.58) | (2.18) | (5.24) | (6.02) | (0.02) | 4.17 | 6.54 | |||||
| Book value | 0.33 | 9.23 | 10.11 | 12.76 | 15.55 | 26.74 | 20.49 | 28.68 | 33.10 | 42.14 | |||||
| Shares, m | 1 | 5 | 11 | 16 | 19 | 22 | 25 | 27 | 29 | 29 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | — | — | — | — | 694.22 | 50.54 | 34.82 | ||||
| P/S | — | — | — | — | — | — | — | 0.00 | 15.42 | 18.34 | |||||
| P/B | — | — | — | — | — | — | — | 4.36 | 4.73 | 5.85 | |||||
| EV/Sales | — | — | — | — | — | — | — | 0.00 | 13.36 | 16.21 | |||||
| EV/FCF | — | — | — | — | — | — | — | (4,744.59) | 32.57 | 33.31 | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (1) | (4) | (9) | (19) | (26) | (48) | (101) | (89) | 123 | 201 | ||||
| Capex | 0 | 0 | (2) | (6) | (15) | (68) | (53) | 88 | (4) | (12) | |||||
| Free cash flow | (1) | (4) | (12) | (25) | (41) | (116) | (154) | (1) | 119 | 189 | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 2 | 49 | 110 | 193 | 260 | 417 | 355 | 555 | 640 | 922 | ||||
| Total debt | 2 | — | — | 3 | 3 | 7 | 7 | — | — | — | |||||
| Net debt | 0 | (50) | (112) | (194) | (271) | (438) | (379) | (532) | (598) | (828) | |||||
| Shareholders’ equity | 0 | 49 | 113 | 203 | 292 | 594 | 522 | 779 | 946 | 1,220 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (4.40) | (30.29) | (13.10) | (11.74) | (12.38) | (14.85) | (23.63) | 1.59 | 9.51 | 17.14 | ||||
| ROIC | (341.81) | 0.00 | (508.36) | (149.54) | (99.05) | (27.45) | (63.43) | (27.80) | 11.78 | 25.73 | |||||
| ROE | (4.76) | (32.76) | (13.39) | (12.08) | (13.00) | (15.71) | (25.09) | 1.68 | 10.34 | 18.91 | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Krystal Biotech, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| BMRN BioMarin Pharmaceutical Inc. | $10.9B | 144× | 16.1× | +19.91% (above 0%: growing) | −81.60% (below 0%: shrinking) | −20.28% (below 0%: shrinking) | 79.51% | 11.21% | Compare |
| MDGL Madrigal Pharmaceuticals, Inc. | $10.6B | — (loss-making) | — (loss-making) | +71.17% (above 0%: growing) | n/m | +140.54% (above 0%: growing) | 89.02% | (15.46%) | Compare |
| IBRX ImmunityBio, Inc. | $10.6B | — (loss-making) | — (loss-making) | +93.91% (above 0%: growing) | n/m | +13.38% (above 0%: growing) | 99.42% | (120.41%) | Compare |
| PCVX Vaxcyte, Inc. | $10.3B | — (loss-making) | — | — | n/m | −92.55% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| KRYS Krystal Biotech, Inc. | $9.8B | 38.3× | 38.6× | +24.14% (above 0%: growing) | +39.10% (above 0%: growing) | +40.14% (above 0%: growing) | 94.60% | 49.00% | |
| KYMR Kymera Therapeutics, Inc. | $9.0B | — (loss-making) | — (loss-making) | +466.40% (above 0%: growing) | n/m | +9.97% (above 0%: growing) | 100.00% | (116.32%) | Compare |
| CAI Caris Life Sciences,�Inc. | $9.0B | 81.3× | 163× | +45.38% (above 0%: growing) | n/m | +8.47% (above 0%: growing) | 68.10% | 10.21% | Compare |
| CYTK Cytokinetics, Incorporated | $8.9B | — (loss-making) | — (loss-making) | −57.13% (below 0%: shrinking) | n/m | −24.02% (below 0%: shrinking) | 80.46% | (625.95%) | Compare |
| PTGX Protagonist Therapeutics, Inc. | $8.8B | 106× | 25.0× | +3,749.17% (above 0%: growing) | n/m | +839.65% (above 0%: growing) | 100.00% | 74.37% | Compare |
| Median of peers | $9.6B | 106× | 25.0× | +71.17% | — | +9.22% | 84.74% | (7.73%) |
Krystal Biotech, Inc. (KRYS) key facts
- Strength: Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024.
- Strength: Net income was $204.8 million, or $7.08 per share (basic), a net margin of 52.6%.
- Krystal Biotech, Inc. (KRYS) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, KRYS traded at $316.58, a market capitalization of $9.8 billion.
- At that price the stock trades at 38.3× trailing-twelve-month earnings and 21.2× sales.
- Return on equity was 18.9% and debt-to-equity 0.00.
- Its Piotroski F-score is 7 out of 9 and its Altman Z-score is 39.03 (safe zone) for fiscal 2025.