Krystal Biotech, Inc.

KRYS Healthcare Biotechnology

Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024. In the quarter to June 2026, revenue grew 24.1%, EPS grew 39.1% and free cash flow grew 40.1%, each against the same quarter a year earlier. Operating cash flow growth for three consecutive years.

316.58 13.42 −4.07%
Market cap
$9.8B
P/E
38.3×
Fwd P/E
38.6×
Dividend yield
—
F-score
7/9
Altman Z
39.03
Beneish M
−2.27
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
Piotroski F-Score
7 — — — — — — — — —
P/E ratio
34.82 50.54 694.22 — — — — — — —
P/S ratio
18.34 15.42 0.00 — — — — — — —
Altman Z-Score
39.03 25.52 50.87 — — — — — — —
P/FCF ratio
37.69 37.58 0.00 — — — — — — —
Altman Z″-Score (non-manufacturers)
16.61 12.92 23.06 — — — — — — —
Beneish M-Score
(2.27) 1.05 — — — — — — — —
P/Operating CF
92.07 84.76 (469.19) — — — — — — —
P/B ratio
5.85 4.73 4.36 — — — — — — —
EV/Sales
16.21 13.36 0.00 — — — — — — —
EV/EBITDA
37.58 53.57 0.00 — — — — — — —
EV/FCF
33.31 32.57 (4,744.59) — — — — — — —
Current Ratio
9.95 7.28 17.76 13.30 17.18 17.80 58.88 43.39 77.99 50.44
Net Debt/EBITDA
(4.93) (8.25) 5.13 2.67 6.69 8.71 9.23 9.49 10.44 0.07
Debt/Equity
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.38
ROE
18.91% 10.34% 1.68% (25.09%) (15.71%) (13.00%) (12.08%) (13.39%) (32.76%) (4.76%)
ROA
17.14% 9.51% 1.59% (23.63%) (14.85%) (12.38%) (11.74%) (13.10%) (30.29%) (4.40%)
ROIC
25.73% 11.78% (27.80%) (63.43%) (27.45%) (99.05%) (149.54%) (508.36%) 0.00% (341.81%)
Return on Tangible Assets
19.10% 11.21% 1.53% (27.09%) (13.15%) (11.07%) (9.50%) (9.63%) (16.01%) (53.76%)
Average Days of Receivables
119.52 131.60 302.66 — — — — — — —
Earnings Yield
2.87% 1.98% 0.14% — — — — — — —
Free Cash Flow Yield
2.65% 2.66% (0.02%) — — — — — — —
Free Cash Flow per Share
6.54 4.17 (0.02) (6.02) (5.24) (2.18) (1.58) (1.04) (0.76) (1.51)
Book value per Share
42.14 33.10 28.68 20.49 26.74 15.55 12.76 10.11 9.23 0.33
Free Cash Flow
189.35 119.18 (0.60) (153.55) (116.27) (40.93) (25.09) (11.68) (4.10) (1.33)
EV/EBIT
39.11 59.04 0.00 — — — — — — —
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