Krystal Biotech, Inc.

KRYS Healthcare Biotechnology

Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024.

Revenue
+30.2%
EPS
−22.3%
Free cash flow
+137.8%

Quarter to September 2026, against a year earlier

300.31 0.06 +0.02%
Market cap
$8.9B
P/E
39.2×
Fwd P/E
45.7×
Dividend yield
—
F-score
7/9
Altman Z
39.03
Beneish M
−2.27
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
Piotroski F-Score
7 — — — — — — — — —
P/E ratio
34.82 50.54 694.22 — — — — — — —
P/S ratio
18.34 15.42 0.00 — — — — — — —
Altman Z-Score
39.03 25.52 50.87 — — — — — — —
P/FCF ratio
37.69 37.58 0.00 — — — — — — —
Altman Z″-Score (non-manufacturers)
16.61 12.92 23.06 — — — — — — —
Beneish M-Score
(2.27) 1.05 — — — — — — — —
P/Operating CF
92.07 84.76 (469.19) — — — — — — —
P/B ratio
5.85 4.73 4.36 — — — — — — —
EV/Sales
16.21 13.36 0.00 — — — — — — —
EV/EBITDA
37.58 53.57 0.00 — — — — — — —
EV/FCF
33.31 32.57 (4,744.59) — — — — — — —
Current Ratio
9.95 7.28 17.76 13.30 17.18 17.80 58.88 43.39 77.99 50.44
Net Debt/EBITDA
(4.93) (8.25) 5.13 2.67 6.69 8.71 9.23 9.49 10.44 0.07
Debt/Equity
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.38
ROE
18.91% 10.34% 1.68% (25.09%) (15.71%) (13.00%) (12.08%) (13.39%) (32.76%) (4.76%)
ROA
17.14% 9.51% 1.59% (23.63%) (14.85%) (12.38%) (11.74%) (13.10%) (30.29%) (4.40%)
ROIC
25.73% 11.78% (27.80%) (63.43%) (27.45%) (99.05%) (149.54%) (508.36%) 0.00% (341.81%)
Return on Tangible Assets
19.10% 11.21% 1.53% (27.09%) (13.15%) (11.07%) (9.50%) (9.63%) (16.01%) (53.76%)
Average Days of Receivables
119.52 131.60 302.66 — — — — — — —
Earnings Yield
2.87% 1.98% 0.14% — — — — — — —
Free Cash Flow Yield
2.65% 2.66% (0.02%) — — — — — — —
Free Cash Flow per Share
6.54 4.17 (0.02) (6.02) (5.24) (2.18) (1.58) (1.04) (0.76) (1.51)
Book value per Share
42.14 33.10 28.68 20.49 26.74 15.55 12.76 10.11 9.23 0.33
Free Cash Flow
189.35 119.18 (0.60) (153.55) (116.27) (40.93) (25.09) (11.68) (4.10) (1.33)
EV/EBIT
39.11 59.04 0.00 — — — — — — —
Other line items

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Columns are period end dates · fundamentals updated 5 Nov 2026