TG Therapeutics, Inc.

TGTX Healthcare Biotechnology

TG Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $616.3 million, up 87.3% from fiscal 2024.

Revenue
+70.3%
EPS
−73.7%
Free cash flow
+427.1%
Total debt
+204.2%

Quarter to June 2026, against a year earlier

58.27 0.29 +0.50%
Market cap
$8.9B
P/E
19.1×
Fwd P/E
62.4×
Dividend yield
—
F-score
5/9
Altman Z
6.29
Beneish M
0.80
Dividend safety
n/a

Revenue by products and services Fiscal 2024

  • Product
  • Milestone
  • Other Revenue
  • Royalty
  • License Revenue

Every year since 2019 →

Insider Decisions last twelve months

Sold, $m 0.27
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — 1 — —
Insider Ownership 0.09%

Capital & Financial Ratios $m

Size
Market Cap 8,870.00
Revenue ttm 799.54
Net income ttm 441.49
Free cash flow ttm 17.39
Net debt Q 193.14
Valuation
P/E 19.11
Forward P/E 62.40 (above 35: high)
Price / sales 10.30 (above 10: high)
Forward P/S Powerpack
Price / FCF 473.79
Price / book 13.64 (above 6: high)
Financial health
Current ratio Q 4.27 (at or above 1.5: strong)
Debt / equity Q 1.23
Interest coverage Q 1.31
Growth
Revenue growth Q +70.27% (above 0%: growing)
Operating income growth Q −37.80% (below 0%: shrinking)
EPS, this year −63.91% (below 0%: weak)
EPS, next year A +187.56% (at or above 15%: strong)
Revenue, next year A +55.82% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A +10.12%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 18.15%
10-year low 10-year high
P/B against its own 10 years 61.77%
10-year low 10-year high
EV/Sales against its own 10 years 19.25%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 218 311 142 552
Receivables 51 129 306 402
Inventory 40 110 126 148
Other 10 16 58 44
318 566 631 1,146
2023 2024 2025 Q'26
Payables 38 58 108 214
ST’ Debt — — — —
Other 1 5 2 1
54 91 154 268

Compound Annual Growth %

10y 5y 3y
Sales 129.45% 426.73% 504.86%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 20.36% 4.53% 122.81%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 0.12 0.05 — — —
’25 0.03 0.17 2.43 0.14 2.77
’24 (0.07) 0.04 0.02 0.15 0.15
’23 (0.28) (0.34) 0.73 (0.09) 0.09
’22 (0.51) (0.30) (0.26) (0.57) (1.65)
’21 (0.69) (0.59) (0.65) (0.70) (2.63)
’20 (0.48) (0.47) (0.73) (0.71) (2.42)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 205 240 — — —
’25 121 141 162 193 616
’24 63 73 84 108 329
’23 8 16 166 44 234
’22 2 1 0 0 3
’21 1 2 2 2 7
’20 0 0 0 0 0
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (18) 39 — — —
’25 (29) 7 (23) 20 (25)
’24 (8) 6 (12) (26) (41)
’23 (60) (42) 84 (13) (31)
’22 (69) (49) (34) (24) (176)
’21 (81) (60) (67) (87) (296)
’20 (62) (44) (57) (52) (215)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (18) 39 — — —
’25 (29) 7 (23) 20 (25)
’24 (8) 6 (12) (26) (41)
’23 (60) (42) 84 (13) (31)
’22 (69) (49) (34) (24) (176)
’21 (81) (60) (67) (87) (296)
’20 (62) (44) (57) (52) (215)
Fiscal quarters ending in the months shown.

Valuation

The price implies free cash flow after share-based pay growing 31.6% a year for ten years.

Implied
31.6%
Open the model

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue 0 0 0 0 0 7 3 234 329 616 800 +151.7% 960 1,319 1,626 +38.2%
Gross margin, % 100.00 100.00 100.00 100.00 100.00 88.19 90.48 93.95 88.30 83.66 82.37 (16.3) pt
EBT (78) (118) (173) (173) (279) (348) (224) 13 26 107 102 n/m
EBT margin, % (51,482.24) (77,944.74) (114,132.89) (113,730.92) (183,803.29) (5,204.08) (8,036.34) 5.59 7.78 17.43 12.71 +51,499.7 pt
Net income (78) (118) (173) (173) (279) (348) (224) 13 23 447 441 n/m
Per share, $
Per share, $ Revenue 0.00 0.00 0.00 0.00 0.00 0.05 0.02 1.65 2.26 4.27 5.64 +123.2%
Earnings (1.60) (1.91) (2.15) (1.96) (2.42) (2.63) (1.65) 0.09 0.16 3.10 3.04 n/m
Cash flow (1.26) (1.51) (1.71) (1.50) (1.86) (2.24) (1.30) (0.22) (0.28) (0.17) 0.13 (19.8%)
Capex (0.01) 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 (15.7%)
Free cash flow (1.26) (1.51) (1.71) (1.50) (1.86) (2.24) (1.30) (0.22) (0.28) (0.17) 0.12 (19.8%)
Book value 0.73 1.08 0.32 0.44 4.50 1.79 0.43 1.13 1.53 4.49 4.26 +22.3%
Shares, m 49 62 75 88 115 132 135 142 145 144 144 +12.7%
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 213.00 177.06 9.71 19.11 40.0
P/S 1,435.74 3,573.11 2,035.62 6,453.26 39,471.54 375.58 562.55 10.35 13.29 6.98 10.30 5,393.8
P/B 6.08 8.11 12.87 25.40 11.55 10.59 26.74 15.07 19.67 6.64 13.64 14.3
EV/Sales 1,141.20 3,016.52 1,583.09 5,731.82 35,702.31 338.65 530.39 9.85 13.10 7.15 10.54 4,807.4
EV/FCF (2.80) (4.89) (1.87) (6.55) (25.26) (7.65) (8.38) (73.26) (106.20) (176.37) 484.96 (41.3)
Cash, $m
Cash, $m Operating cash flow (62) (94) (129) (133) (215) (296) (176) (31) (41) (25) 18 (9.6%)
Capex 0 0 0 0 0 0 0 — 0 0 0 (5.1%)
Free cash flow (62) (94) (129) (133) (215) (296) (176) (31) (41) (25) 17 (9.6%)
Balance, $m
Balance, $m Working capital 34 65 40 65 524 266 115 264 476 477 877 +34.1%
Net debt (45) (85) (69) (110) (573) (247) (91) (117) (67) 104 193 n/m
Shareholders’ equity 36 67 24 39 519 237 59 161 222 648 604 +37.9%
Returns, %
Returns, % ROA (93.02) (155.72) (191.70) (140.19) (70.85) (69.26) (78.09) 4.84 5.15 54.50 37.70 +147.5 pt
ROIC 0.00 0.00 0.00 0.00 0.00 0.00 0.00 29.91 16.82 10.25 10.69 +10.3 pt
ROE (113.87) (230.36) (381.16) (551.85) (100.14) (92.03) (151.36) 11.57 12.21 102.75 100.28 +216.6 pt
People
People Employees 64 75 105 134 272 286 226 264 338 399 — +22.5%
Revenue/emp, $m 0.00 0.00 0.00 0.00 0.00 0.02 0.01 0.89 0.97 1.54 — +105.4%
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026 · fundamentals updated 25 Oct 2026

Business profile

Updated

TG Therapeutics is a biotechnology company that acquires, develops and sells treatments for diseases involving B cells, a type of immune cell. Its primary focus is multiple sclerosis (MS), a disease in which the immune system damages the central nervous system. The company was incorporated in Delaware in 1993. Its headquarters is listed in New York City, while its executive offices are in Morrisville, North Carolina. Michael Weiss is chairman and chief executive officer.

Its approved medicine, BRIUMVI, treats adults with relapsing forms of MS. It is an antibody that targets CD20, a protein on B cells. After the starting dose, BRIUMVI can be given as a one-hour intravenous infusion every 24 weeks. Physicians and patients can access it in the United States, and it is also available in several countries outside the U.S.

Where the money comes from and where it goes Fiscal 2024

Fiscal 2024: revenue by products and services, and margins
Product 314 95.36%
Milestone 13 3.80%
Other Revenue 2 0.55%
Royalty 1 0.24%
License Revenue 0 0.05%
Gross margin 88.30%
Operating margin 12.74%
Pre-tax margin 7.78%

Revenue by segment since 2019

TG Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
MDGL Madrigal Pharmaceuticals, Inc. $9.3B — (loss-making) — (loss-making) +50.13% (above 0%: growing) n/m +53.47% (above 0%: growing) 91.23% 12.98% Compare
SYRE Spyre Therapeutics, Inc. $9.2B — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −108.79% (below 0%: shrinking) 0.00% 0.00% Compare
KRYS Krystal Biotech, Inc. $8.9B 39.2× 45.7× +30.21% (above 0%: growing) −22.26% (below 0%: shrinking) +137.79% (above 0%: growing) 94.07% 55.87% Compare
TGTX TG Therapeutics, Inc. $8.9B 19.1× 62.4× +70.27% (above 0%: growing) −73.68% (below 0%: shrinking) +427.05% (above 0%: growing) 82.86% 9.02%
PTGX Protagonist Therapeutics, Inc. $8.8B 111× 31.2× +3,749.17% (above 0%: growing) n/m +839.65% (above 0%: growing) 100.00% 74.37% Compare
IBRX ImmunityBio, Inc. $8.5B — (loss-making) — (loss-making) +93.91% (above 0%: growing) n/m +13.38% (above 0%: growing) 99.42% (120.41%) Compare
TWST Twist Bioscience Corporation $7.9B — (loss-making) — (loss-making) +23.24% (above 0%: growing) n/m −7.23% (below 0%: shrinking) 52.76% (30.65%) Compare
CYTK Cytokinetics, Incorporated $7.7B — (loss-making) — (loss-making) +2,356.46% (above 0%: growing) n/m −6.73% (below 0%: shrinking) 0.00% (351.34%) Compare
CAI Caris Life Sciences,�Inc. $7.4B 77.7× 254× +26.99% (above 0%: growing) −40.33% (below 0%: shrinking) −140.21% (below 0%: shrinking) 0.00% 7.01% Compare
Median of peers $8.6B 77.7× 45.7× +40.17% — +3.33% 72.00% 3.51%

All 621 Biotechnology stocks →

From the latest earnings call

Updated

  • CEO Michael Weiss said new BRIUMVI patient starts grew and physician adoption expanded, while a subcutaneous formulation could reach patients who prefer self-administered treatment.
  • Chief Commercial Officer Adam Waldman said TG Therapeutics raised its annual guidance based on first-half performance and expects the fourth quarter to drive second-half growth.

Largest institutional holders 13F, quarter to 30 June 2026

Held by institutions 72.58%
Held by the ten largest 42.91%
Holder Shares Stake Change
BlackRock 22.05m 14.40% −202.88k
Vanguard 15.33m 10.01% −768.54k
State Street 7.79m 5.09% −863.29k
Geode Capital Management 3.64m 2.38% +142.30k
D. E. Shaw 3.40m 2.22% +2.81m
Soleus Capital Management, L.P. 2.93m 1.91% −1.10m
T. Rowe Price 2.77m 1.81% +2.13m
Franklin Templeton 2.72m 1.78% −576.07k
CONGRESS ASSET MANAGEMENT CO 2.60m 1.70% +432.04k
Two Sigma 2.47m 1.61% +926.66k
13F filings for the quarter to 30 June 2026: long positions in US-listed shares reported by managers with $100m or more, ~45 days after the quarter.

Pay and ownership Proxy statement filed 30 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 25.57m 28.30m 57.00
2024 18.75m 91.74m 58.00
2023 18.47m 41.18m 33.00
2022 10.44m (42.94m) 23.00
2021 42.67m (114.07m) 37.00

Ownership

Directors and executive officers, together 8.87%
5% Stockholders Blackrock, Inc. 13.15%
Vanguard Group, Inc. 10.19%
Michael S. Weiss 7.54%
State Street Corporation 5.29%
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

TG Therapeutics, Inc. (TGTX) Latest News

18 Sep

10 Aug

Impact 4 · · The Motley Fool transcript

TGTX metrics, ten years each

stockrow.com/TGTX · Data as of Oct 25, 2026 · For information only; not investment advice. · © 2026 stockrow.com