Protagonist Therapeutics, Inc.

PTGX Healthcare Biotechnology

Protagonist Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, down 89.4% from fiscal 2024.

Revenue
+3,749.2%
EPS
+549.1%
Free cash flow
+839.7%

Quarter to June 2026, against a year earlier

132.51 2.75 −2.03%
Market cap
$8.8B
P/E
111×
Fwd P/E
31.2×
Dividend yield
—
F-score
4/9
Altman Z
61.55
Beneish M
−7.18
Dividend safety
n/a

Protagonist Therapeutics, Inc. (PTGX) Return on assets

Alert me on Return on assets

Protagonist Therapeutics, Inc.'s return on assets over the twelve months to 30 June 2026 was 10.3%, up 28.8 percentage points from fiscal 2025 (−18.4%). Over the past ten years it has ranged from −118.1% (fiscal 2015) to 49.9% (fiscal 2024); the current reading is higher than 91% of that period. That is above the Biotechnology industry median of −45.6% and above the Healthcare sector median of −29.3%.

Return on assets, annual

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Annual newest first

Period Return on assets Change (points)
FY2025 −18.4% (68.33)
FY2024 49.9% 75.97
FY2023 −26.1% 16.72
FY2022 −42.8% (5.42)
FY2021 −37.4% (9.76)
FY2020 −27.6% 24.84
FY2019 −52.4% (26.77)
FY2018 −25.7% 3.01
FY2017 −28.7% 40.66
FY2016 −69.3% 48.71

Against its own ten years

Low −118.1% High 49.9%
Ten-year median −28.7%
Current reading's percentile 91

Return on assets against peers

Company Return on assets
TGTX TG Therapeutics, Inc. compare 37.7%
KRYS Krystal Biotech, Inc. compare 15.9%
PTGX Protagonist Therapeutics, Inc. 10.3%
CAI Caris Life Sciences,�Inc. compare 8.58%
MDGL Madrigal Pharmaceuticals, Inc. compare −11.1%
TWST Twist Bioscience Corporation compare −20.8%
SYRE Spyre Therapeutics, Inc. compare −30.9%
CYTK Cytokinetics, Incorporated compare −47.7%
IBRX ImmunityBio, Inc. compare −192.6%
Biotechnology industry median −45.6%
Healthcare sector median −29.3%
Market median 0.00%

What Return on assets is

ROA tells an investor how much profit a company earns for shareholders from the assets it uses to run its business.

Annual: Net Income Allotted to Shareholders ÷ Average Assets; TTM: Net Income Allotted to Shareholders ÷ Average Assets (latest quarter)

The full definition of Return on assets →

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