Ascendis Pharma A/S

ASND Healthcare Biotechnology

Ascendis Pharma A/S’s revenue for fiscal 2025 (year ended December 2025) was $814.8 million, up 107.1% from fiscal 2024.

Revenue
+119.9%
EPS
+612.3%
Free cash flow
+2,335.9%
Total debt
−41.8%

Quarter to June 2026, against a year earlier

256.42 2.97 +1.17%
Market cap
$16.6B
P/E
18.3×
Fwd P/E
15.4×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.51
Dividend safety
n/a

Ascendis Pharma A/S (ASND) Operating margin

Alert me on Operating margin

Ascendis Pharma A/S's operating margin over the twelve months to 30 June 2026 was 24.8%, up 43.8 percentage points from fiscal 2025 (−18.9%). Over the past ten years it has ranged from −7,290.1% (fiscal 2017) to −18.9% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −18.9% 57.74
FY2024 −76.7% 94.13
FY2023 −170.8% 927.06
FY2022 −1,097.9% 4,710.71
FY2021 −5,808.6% (1,053.48)
FY2020 −4,755.1% (3,059.98)
FY2019 −1,695.1% (232.51)
FY2018 −1,462.6% 5,827.50
FY2017 −7,290.1% (5,706.94)
FY2016 −1,583.2% (1,067.94)

Quarterly newest first

Period Operating margin Change (points)
Jun 2026 65.0% 54.92
Mar 2026 10.1% 9.03
Dec 2025 1.03% (4.12)
Sep 2025 5.15% 38.65
42 more quarters

Against its own ten years

Low −7,290.1% High −18.9%
Ten-year median −1,462.6%
Current reading's percentile 100

Operating margin against peers

Company Operating margin
EXEL Exelixis, Inc. compare 40.2%
HALO Halozyme Therapeutics, Inc. compare 37.4%
ASND Ascendis Pharma A/S 24.8%
ALNY Alnylam Pharmaceuticals, Inc. compare 19.5%
JAZZ Jazz Pharmaceuticals PLC compare 9.03%
SMMT Summit Therapeutics PLC compare 0.00%
INSM Insmed, Inc. compare −37.1%
BBIO BridgeBio Pharma, Inc. compare −38.5%
BNTX BioNTech SE Sponsored ADR compare −79.0%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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