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Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024. In the quarter to June 2026, revenue grew 12.5%, EPS grew 7.96% and free cash flow grew 9.25%, each against the same quarter a year earlier. Member of the S&P 500 and Nasdaq 100; revenue growth for ten consecutive years.

499.39 9.36 −1.84%
Market cap
$129.0B
P/E
28.8×
Fwd P/E
25.5×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a
Overview Business Profile Financial Analysis Income Statement Balance Sheet Cash Flow Metrics & Ratios Filings 10-Q 10-K

Vertex Pharmaceuticals Incorporated (VRTX) P/E ratio

Alert me on P/E ratio

As of 16 October 2026, Vertex Pharmaceuticals Incorporated (VRTX) trades at a P/E ratio of 28.8×. Over the past ten years it has ranged from 0.0× (June 2025) to 194× (October 2017); the current reading is higher than 69% of that period. That is above the Biotechnology industry median of 8.5× and above the Healthcare sector median of 23.0×.

P/E ratio, daily

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Annual newest first

Period P/E ratio Change
FY2025 29.3× —
FY2024 0.0× —
FY2023 29.3× 32.82%
FY2022 22.0× (8.69%)
FY2021 24.1× 6.40%
FY2020 22.7× (52.66%)
FY2019 47.9× 138.24%
FY2018 20.1× (85.93%)
FY2017 143× —
FY2016 0.0× —

Quarterly newest first

Period P/E ratio Change
Jun 2026 28.7× 9.19%
Mar 2026 26.3× (10.42%)
Dec 2025 29.3× 7.23%
Sep 2025 27.3× (13.20%)
42 more quarters

Against its own ten years

Low 0.0× High 194×
Ten-year median 24.9×
Current reading's percentile 57

P/E ratio against peers

Company P/E ratio
ROIV Roivant Sciences Ltd. compare n/m
MRNA Moderna, Inc. compare n/m
RVMD Revolution Medicines, Inc. compare n/m
REGN Regeneron Pharmaceuticals, Inc. compare 18.9×
VRTX Vertex Pharmaceuticals Incorporated 28.8×
ARGX argenex SE compare 29.6×
ALNY Alnylam Pharmaceuticals, Inc. compare 39.5×
RPRX Royalty Pharma PLC compare 42.3×
ONC BeOne Medicines Ltd. - Sponsored ADR compare 62.6×
Biotechnology industry median 8.5×
Healthcare sector median 23.0×
Market median 18.1×

What P/E ratio is

Price to Earnings Ratio shows how much investors pay for each dollar of a company’s annual profit per share.

Stock Price ÷ EPS (Basic) (TTM)

The full definition of P/E ratio →

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