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Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024.

Revenue
+11.9%
EPS
−39.2%
Free cash flow
−52.1%

Quarter to September 2026, against a year earlier

547.19 4.69 +0.86%
Market cap
$137.5B
P/E
34.6×
Fwd P/E
33.2×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a
Overview Business Profile Earnings & Analysis
Financials
Income Statement Balance Sheet Cash Flow Metrics & Ratios
Segments Valuation Filings

Vertex Pharmaceuticals Incorporated (VRTX) EV/FCF

Alert me on EV/FCF

As of 5 November 2026, Vertex Pharmaceuticals Incorporated (VRTX) trades at a EV/FCF of 42.1×. Over the past ten years it has ranged from −440× (August 2016) to 347× (November 2016); the current reading is higher than 83% of that period.

EV/FCF, daily

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Annual newest first

Period EV/FCF Change
FY2025 34.4× —
FY2024 −100× —
FY2023 28.6× 77.46%
FY2022 16.1× (22.25%)
FY2021 20.7× 11.54%
FY2020 18.6× (47.90%)
FY2019 35.6× 5.05%
FY2018 33.9× (31.37%)
FY2017 49.4× (49.76%)
FY2016 98.4× —

Quarterly newest first

Period EV/FCF Change
Sep 2026 40.6× 29.99%
Jun 2026 31.2× 8.69%
Mar 2026 28.7× (16.35%)
Dec 2025 34.4× 21.68%
43 more quarters

Against its own ten years

Low −440× High 347×
Ten-year median 25.7×
Current reading's percentile 77

EV/FCF against peers

Company EV/FCF
MRNA Moderna, Inc. compare −73.7×
ROIV Roivant Sciences Ltd. compare −28.1×
RVMD Revolution Medicines, Inc. compare −25.0×
GMAB Genmab A/S Sponsored ADR compare −5.7×
REGN Regeneron Pharmaceuticals, Inc. compare 23.7×
ONC BeOne Medicines Ltd. - Sponsored ADR compare 27.1×
RPRX Royalty Pharma PLC compare 29.5×
ARGX argenex SE compare 38.4×
VRTX Vertex Pharmaceuticals Incorporated 42.1×

What EV/FCF is

EV/Free CF shows how the value of a whole company, debt included, compares with the free cash its business produces.

((Stock Price × Shares (Basic, Weighted) (latest quarter)) + (Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter)) − Cash & Short Term Investments (latest quarter)) ÷ (Operating Cash Flow (TTM) + Property, Plant, Equipment Change (Net) (TTM) + Intangible Assets Change (Net) (TTM))

The full definition of EV/FCF →

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