argenex SE (ARGX) vs Vertex Pharmaceuticals Incorporated (VRTX)

argenex SE and Vertex Pharmaceuticals Incorporated are both Biotechnology companies. Vertex Pharmaceuticals Incorporated is the larger, with a market value of $132.3B against $60.2B — 2.2× the size. Vertex Pharmaceuticals Incorporated trades at the lower P/E: 30.4× against 34.6×. argenex SE grew revenue faster over the last twelve months: 70.6% against 10.2%. Vertex Pharmaceuticals Incorporated has the higher net margin (35.0% vs 32.2%) and the higher return on invested capital (24.1% vs 20.7%). Across the 21 metrics below, Vertex Pharmaceuticals Incorporated leads on 14 and argenex SE on 7.

Valuation

Metric ARGX VRTX Biotechnology median
P/E 34.61 30.36 7.88
P/S 11.22 10.61 11.47
P/B 7.10 6.59 2.52
Price to free cash flow 43.37 35.17 21.16
EV/EBITDA 35.09 25.17 0.74
EV/Sales 10.55 10.00 10.73
Earnings yield 2.89% 3.29% (28.84%)
Free cash flow yield 2.31% 2.84% (23.03%)

Profitability

Metric ARGX VRTX Biotechnology median
Gross margin 90.15% 86.00% 65.16%
Operating margin 30.06% 37.95% 0.00%
Net margin 32.20% 35.00% 0.00%
Free cash flow margin 25.87% 30.16% 0.00%
Return on equity 27.07% 23.54% (57.72%)
Return on assets 19.95% 17.12% (49.22%)
Return on invested capital 20.71% 24.09% 0.00%

Growth

Metric ARGX VRTX Biotechnology median
Revenue growth (TTM) 70.58% 10.23% 5.64%
EPS growth (last fiscal year) 53.13% 836.54% —
Revenue growth, 5-year CAGR 130.77% 14.10% 8.40%
Net income growth, 5-year CAGR 0.00% 7.83% 0.00%

Health

Metric ARGX VRTX Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 5.12 3.19 4.73
Net debt to EBITDA (3.23) (1.51) 0.96

Dividend

Metric ARGX VRTX Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric ARGX VRTX Biotechnology median
Market cap 60.20b 132.32b 162.10m

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