Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024.

Revenue
+11.9%
EPS
−39.2%
Free cash flow
−52.1%

Quarter to September 2026, against a year earlier

546.45 3.95 +0.73%
Market cap
$137.5B
P/E
34.6×
Fwd P/E
33.2×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a

Vertex Pharmaceuticals Incorporated (VRTX) Net margin

Alert me on Net margin

Vertex Pharmaceuticals Incorporated's net margin over the twelve months to 30 September 2026 was 30.7%, down 2.2 percentage points from fiscal 2025 (32.9%). Over the past ten years it has ranged from −53.9% (fiscal 2015) to 68.8% (fiscal 2018); the current reading is higher than 64% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Net margin, annual

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Annual newest first

Period Net margin Change (points)
FY2025 32.9% 37.80
FY2024 −4.86% (41.54)
FY2023 36.7% (0.52)
FY2022 37.2% 6.28
FY2021 30.9% (12.78)
FY2020 43.7% 15.43
FY2019 28.3% (40.53)
FY2018 68.8% 58.21
FY2017 10.6% 17.17
FY2016 −6.58% 47.31

Quarterly newest first

Period Net margin Change (points)
Sep 2026 19.0% (13.99)
Jun 2026 33.0% (1.54)
Mar 2026 34.5% (2.81)
Dec 2025 37.3% 2.14
43 more quarters

Against its own ten years

Low −53.9% High 68.8%
Ten-year median 30.9%
Current reading's percentile 44

Net margin against peers

Company Net margin
ARGX argenex SE compare 31.7%
VRTX Vertex Pharmaceuticals Incorporated 30.7%
REGN Regeneron Pharmaceuticals, Inc. compare 28.5%
GMAB Genmab A/S Sponsored ADR compare 19.1%
ONC BeOne Medicines Ltd. - Sponsored ADR compare 13.9%
RPRX Royalty Pharma PLC compare 0.00%
MRNA Moderna, Inc. compare −141.4%
RVMD Revolution Medicines, Inc. compare −894.4%
ROIV Roivant Sciences Ltd. compare −3,535.0%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 1.06%

What Net margin is

Net Profit Margin tells an investor how much of each unit of revenue ends up as profit for shareholders after all costs, interest and taxes.

Net Income Allotted to Shareholders ÷ Revenue

The full definition of Net margin →

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