Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024.

Revenue
+11.9%
EPS
−39.2%
Free cash flow
−52.1%

Quarter to September 2026, against a year earlier

547.29 4.79 +0.88%
Market cap
$137.5B
P/E
34.6×
Fwd P/E
33.2×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a

Vertex Pharmaceuticals Incorporated (VRTX) Gross margin

Alert me on Gross margin

Vertex Pharmaceuticals Incorporated's gross margin over the twelve months to 30 September 2026 was 85.5%, down 0.7 percentage points from fiscal 2025 (86.2%). Over the past ten years it has ranged from 86.1% (fiscal 2024) to 89.0% (fiscal 2017); the current reading is higher than 18% of that period. That is above the Biotechnology industry median of 65.2% and above the Healthcare sector median of 53.9%.

Gross margin, annual

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Annual newest first

Period Gross margin Change (points)
FY2025 86.2% 0.13
FY2024 86.1% (1.10)
FY2023 87.2% (0.69)
FY2022 87.9% (0.16)
FY2021 88.1% (0.08)
FY2020 88.1% 1.30
FY2019 86.8% 0.28
FY2018 86.6% (2.39)
FY2017 89.0% 1.31
FY2016 87.6% (0.30)

Quarterly newest first

Period Gross margin Change (points)
Sep 2026 84.7% (0.62)
Jun 2026 85.3% (1.52)
Mar 2026 86.9% 1.46
Dec 2025 85.4% (1.13)
43 more quarters

Against its own ten years

Low 86.1% High 89.0%
Ten-year median 87.6%
Current reading's percentile 2

Gross margin against peers

Company Gross margin
RPRX Royalty Pharma PLC compare 100.0%
RVMD Revolution Medicines, Inc. compare 95.6%
GMAB Genmab A/S Sponsored ADR compare 93.0%
ARGX argenex SE compare 90.2%
ONC BeOne Medicines Ltd. - Sponsored ADR compare 89.4%
REGN Regeneron Pharmaceuticals, Inc. compare 85.8%
VRTX Vertex Pharmaceuticals Incorporated 85.5%
ROIV Roivant Sciences Ltd. compare 81.2%
MRNA Moderna, Inc. compare 23.4%
Biotechnology industry median 65.2%
Healthcare sector median 53.9%
Market median 45.1%

What Gross margin is

Gross Margin tells an investor how much of each sale a company keeps after paying the direct costs of making or buying what it sells.

Gross Profit ÷ Revenue

The full definition of Gross margin →

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