Vertex Pharmaceuticals Incorporated VRTX
- Market cap
- $132.3B
- P/E
- 30.4×
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Vertex Pharmaceuticals Incorporated (VRTX) EV/EBITDA
As of 25 September 2026, Vertex Pharmaceuticals Incorporated (VRTX) trades at a EV/EBITDA of 25.2×. Over the past ten years it has ranged from 0.0× (June 2025) to 938× (June 2018); the current reading is higher than 63% of that period. That is above the Biotechnology industry median of 0.7× and above the Healthcare sector median of 10.4×.
EV/EBITDA, daily
Annual
| Period | EV/EBITDA | Change |
|---|---|---|
| FY2025 | 25.0× | — |
| FY2024 | 0.0× | — |
| FY2023 | 23.7× | 67.68% |
| FY2022 | 14.1× | (17.22%) |
| FY2021 | 17.1× | (8.47%) |
| FY2020 | 18.7× | (54.07%) |
| FY2019 | 40.6× | (27.88%) |
| FY2018 | 56.3× | (71.78%) |
| FY2017 | 200× | (19.40%) |
| FY2016 | 248× | — |
Quarterly
| Period | EV/EBITDA | Change |
|---|---|---|
| Jun 2026 | 23.7× | 8.99% |
| Mar 2026 | 21.7× | (13.05%) |
| Dec 2025 | 25.0× | 11.46% |
| Sep 2025 | 22.4× | (14.49%) |
| 42 more quarters | Free account |
Against its own ten years
EV/EBITDA against peers
| Company | EV/EBITDA |
|---|---|
| INSM Insmed, Inc. compare | n/m |
| RVMD Revolution Medicines, Inc. compare | n/m |
| MRNA Moderna, Inc. compare | n/m |
| REGN Regeneron Pharmaceuticals, Inc. compare | 17.3× |
| RPRX Royalty Pharma PLC compare | 22.0× |
| VRTX Vertex Pharmaceuticals Incorporated | 25.2× |
| ALNY Alnylam Pharmaceuticals, Inc. compare | 30.3× |
| ONC BeOne Medicines Ltd. - Sponsored ADR compare | 34.1× |
| ARGX argenex SE compare | 35.1× |
| Biotechnology industry median | 0.7× |
| Healthcare sector median | 10.4× |
| Market median | 11.0× |
What EV/EBITDA is
Enterprise Value over EBITDA tells an investor how the market values a whole company, with debt added and cash taken off, against its operating earnings.
((Stock Price × Shares (Basic, Weighted) (latest quarter)) + (Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter)) − Cash & Short Term Investments (latest quarter)) ÷ EBITDA (TTM)
More on VRTX
- Revenue
- Net income
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Operating margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/Sales
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- The full statement