Revolution Medicines, Inc. (RVMD) vs Vertex Pharmaceuticals Incorporated (VRTX)

Revolution Medicines, Inc. and Vertex Pharmaceuticals Incorporated are both Biotechnology companies. Vertex Pharmaceuticals Incorporated is the larger, with a market value of $132.3B against $42.9B — 3.1× the size. Revolution Medicines, Inc. has negative trailing earnings, so its P/E is not meaningful; Vertex Pharmaceuticals Incorporated trades at 30.4×. Vertex Pharmaceuticals Incorporated grew revenue faster over the last twelve months: 10.2% against −8.81%. Vertex Pharmaceuticals Incorporated has the higher net margin (35.0% vs 0.00%) and the higher return on invested capital (24.1% vs 0.00%). Across the 19 metrics below, Vertex Pharmaceuticals Incorporated leads on 18 and Revolution Medicines, Inc. on 1.