Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024.

Revenue
+11.9%
EPS
−39.2%
Free cash flow
−52.1%

Quarter to September 2026, against a year earlier

547.19 4.69 +0.86%
Market cap
$137.5B
P/E
34.6×
Fwd P/E
33.2×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a

Vertex Pharmaceuticals Incorporated (VRTX) P/S ratio

Alert me on P/S ratio

As of 5 November 2026, Vertex Pharmaceuticals Incorporated (VRTX) trades at a P/S ratio of 10.6×. Over the past ten years it has ranged from 6.4× (October 2021) to 54.4× (March 2015); the current reading is higher than 40% of that period. That is above the Biotechnology industry median of 9.2× and above the Healthcare sector median of 3.5×.

P/S ratio, daily

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Annual newest first

Period P/S ratio Change
FY2025 9.7× 2.49%
FY2024 9.4× (12.16%)
FY2023 10.7× 30.82%
FY2022 8.2× 9.78%
FY2021 7.5× (24.49%)
FY2020 9.9× (26.72%)
FY2019 13.5× (2.35%)
FY2018 13.8× (9.57%)
FY2017 15.3× 42.04%
FY2016 10.8× (63.40%)

Quarterly newest first

Period P/S ratio Change
Sep 2026 10.2× 2.21%
Jun 2026 10.0× 7.81%
Mar 2026 9.3× (3.86%)
Dec 2025 9.7× 13.12%
43 more quarters

Against its own ten years

Low 6.4× High 54.4×
Ten-year median 11.8×
Current reading's percentile 44

P/S ratio against peers

Company P/S ratio
REGN Regeneron Pharmaceuticals, Inc. compare 5.4×
ONC BeOne Medicines Ltd. - Sponsored ADR compare 6.6×
GMAB Genmab A/S Sponsored ADR compare 7.9×
ARGX argenex SE compare 9.5×
VRTX Vertex Pharmaceuticals Incorporated 10.6×
RPRX Royalty Pharma PLC compare 11.5×
MRNA Moderna, Inc. compare 43.2×
RVMD Revolution Medicines, Inc. compare 185×
ROIV Roivant Sciences Ltd. compare 3,528×
Biotechnology industry median 9.2×
Healthcare sector median 3.5×
Market median 1.9×

What P/S ratio is

Price to Sales Ratio shows how much investors pay for each dollar of a company’s annual sales, whether or not it is profitable.

(Stock Price × Shares (Basic, Weighted) (latest quarter)) ÷ Revenue (TTM)

The full definition of P/S ratio →

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