Moderna, Inc. (MRNA) vs Vertex Pharmaceuticals Incorporated (VRTX)

Moderna, Inc. and Vertex Pharmaceuticals Incorporated are both Biotechnology companies. Vertex Pharmaceuticals Incorporated is the larger, with a market value of $132.3B against $78.8B — 1.7× the size. Moderna, Inc. has negative trailing earnings, so its P/E is not meaningful; Vertex Pharmaceuticals Incorporated trades at 30.4×. Vertex Pharmaceuticals Incorporated grew revenue faster over the last twelve months: 10.2% against −27.6%. Vertex Pharmaceuticals Incorporated has the higher net margin (35.0% vs −141.4%) and the higher return on invested capital (24.1% vs −93.5%). Across the 19 metrics below, Vertex Pharmaceuticals Incorporated leads on 18 and Moderna, Inc. on 1.