Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024. In the quarter to June 2026, revenue grew 12.5%, EPS grew 7.96% and free cash flow grew 9.25%, each against the same quarter a year earlier. Member of the S&P 500 and Nasdaq 100; revenue growth for ten consecutive years.

499.39 9.36 −1.84%
Market cap
$129.0B
P/E
28.8×
Fwd P/E
25.5×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a

Vertex Pharmaceuticals Incorporated (VRTX) Operating margin

Alert me on Operating margin

Vertex Pharmaceuticals Incorporated's operating margin over the twelve months to 30 June 2026 was 38.0%, up 3.2 percentage points from fiscal 2025 (34.8%). Over the past ten years it has ranged from −45.2% (fiscal 2015) to 48.2% (fiscal 2022); the current reading is higher than 64% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

Embed this chart

Annual newest first

Period Operating margin Change (points)
FY2025 34.8% 36.88
FY2024 −2.11% (40.94)
FY2023 38.8% (9.40)
FY2022 48.2% 11.50
FY2021 36.7% (9.30)
FY2020 46.0% 17.26
FY2019 28.8% 7.93
FY2018 20.8% 15.89
FY2017 4.95% 4.37
FY2016 0.58% 45.81

Quarterly newest first

Period Operating margin Change (points)
Jun 2026 37.4% (0.70)
Mar 2026 38.1% 0.30
Dec 2025 37.8% (0.76)
Sep 2025 38.6% (0.27)
42 more quarters

Against its own ten years

Low −45.2% High 48.2%
Ten-year median 28.8%
Current reading's percentile 69

Operating margin against peers

Company Operating margin
RPRX Royalty Pharma PLC compare 59.6%
VRTX Vertex Pharmaceuticals Incorporated 38.0%
ARGX argenex SE compare 30.1%
REGN Regeneron Pharmaceuticals, Inc. compare 24.7%
ALNY Alnylam Pharmaceuticals, Inc. compare 20.8%
ONC BeOne Medicines Ltd. - Sponsored ADR compare 15.1%
RVMD Revolution Medicines, Inc. compare 0.00%
MRNA Moderna, Inc. compare −149.0%
ROIV Roivant Sciences Ltd. compare −7,914.8%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

More on VRTX