Insmed, Inc.

INSM Healthcare Biotechnology

Insmed, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $606.4 million, up 66.7% from fiscal 2024.

Revenue
+268.4%
EPS
+73.8%
Free cash flow
+81.1%
Total debt
+0.27%

Quarter to September 2026, against a year earlier

111.86 3.10 +2.85%
Market cap
$23.9B
P/E
0.0×
Fwd P/E
−64.6×
Dividend yield
—
F-score
4/9
Altman Z
9.29
Beneish M
−1.90
Dividend safety
n/a

Insmed, Inc. (INSM) Operating margin

Alert me on Operating margin

Insmed, Inc.'s operating margin over the twelve months to 30 September 2026 was −37.1%, up 168.5 percentage points from fiscal 2025 (−205.6%). Over the past ten years it has ranged from −3,124.9% (fiscal 2018) to 0.00% (fiscal 2017); the current reading is higher than 36% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −205.6% 35.88
FY2024 −241.5% (8.96)
FY2023 −232.5% (46.12)
FY2022 −186.4% 12.64
FY2021 −199.0% (37.71)
FY2020 −161.3% 11.06
FY2019 −172.4% 2,952.56
FY2018 −3,124.9% (3,124.94)
FY2017 0.00% 0.00
FY2016 0.00% 0.00

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 −17.0% (16.68)
Jun 2026 −0.36% 49.75
Mar 2026 −50.1% 71.08
Dec 2025 −121.2% 135.94
43 more quarters

Against its own ten years

Low −3,124.9% High 0.00%
Ten-year median −186.4%
Current reading's percentile 100

Operating margin against peers

Company Operating margin
EXEL Exelixis, Inc. compare 40.2%
GMAB Genmab A/S Sponsored ADR compare 26.0%
ASND Ascendis Pharma A/S compare 24.8%
ALNY Alnylam Pharmaceuticals, Inc. compare 19.5%
INCY Incyte Corporation compare 10.4%
INSM Insmed, Inc. −37.1%
BBIO BridgeBio Pharma, Inc. compare −38.5%
BNTX BioNTech SE Sponsored ADR compare −79.0%
ROIV Roivant Sciences Ltd. compare −7,914.8%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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