stockrowProtagonist Therapeutics, Inc.
PTGX Healthcare Biotechnology
Protagonist Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, down 89.4% from fiscal 2024.
- Revenue
- +3,749.2%
- EPS
- +549.1%
- Free cash flow
- +839.7%
Quarter to June 2026, against a year earlier
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Protagonist Therapeutics, Inc. (PTGX) Free cash flow margin
Protagonist Therapeutics, Inc.'s free cash flow margin over the twelve months to 30 June 2026 was 46.3%, down 75.6 percentage points from fiscal 2025 (121.9%). Over the past ten years it has ranged from −18,395.7% (fiscal 2019) to 121.9% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.
Free cash flow margin, annual
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Annual newest first
| Period | Free cash flow margin | Change (points) |
|---|---|---|
| FY2025 | 121.9% | 79.79 |
| FY2024 | 42.1% | 160.16 |
| FY2023 | −118.1% | 291.73 |
| FY2022 | −409.8% | (11.50) |
| FY2021 | −398.3% | (143.47) |
| FY2020 | −254.8% | 18,140.83 |
| FY2019 | −18,395.7% | (18,232.59) |
| FY2018 | −163.1% | (179.06) |
| FY2017 | 16.0% | 15.98 |
| FY2016 | 0.00% | 0.00 |
Against its own ten years
Free cash flow margin against peers
| Company | Free cash flow margin |
|---|---|
| KRYS Krystal Biotech, Inc. compare | 66.0% |
| PTGX Protagonist Therapeutics, Inc. | 46.3% |
| CAI Caris Life Sciences,�Inc. compare | 8.00% |
| TGTX TG Therapeutics, Inc. compare | 2.17% |
| SYRE Spyre Therapeutics, Inc. compare | 0.00% |
| MDGL Madrigal Pharmaceuticals, Inc. compare | −11.8% |
| TWST Twist Bioscience Corporation compare | −22.2% |
| IBRX ImmunityBio, Inc. compare | −173.8% |
| CYTK Cytokinetics, Incorporated compare | −519.5% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 0.00% |
What Free cash flow margin is
Free Cash Flow Margin tells an investor how much of each sale turns into cash the company keeps after paying for investment in its assets.
(Operating Cash Flow + Property, Plant, Equipment Change (Net) + Intangible Assets Change (Net)) ÷ Revenue
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- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Operating margin
- Net margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
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- Current ratio
- Total debt
- Shares outstanding
- Book value per share
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- Piotroski F-score
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