Xeris Biopharma Holdings, Inc.

XERS Healthcare Drug Manufacturers Specialty & Generic

Xeris Biopharma Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $291.8 million, up 43.7% from fiscal 2024. In the quarter to June 2026, revenue grew 28.7%, EPS fell 1,700.0%, free cash flow grew 8,403.1% and total debt rose 15.5%, each against the same quarter a year earlier. Revenue growth for five consecutive years, operating cash flow growth for three.

10.31 0.24 +2.38%
Market cap
$1.8B
P/E
0.0×
Fwd P/E
54.5×
Dividend yield
—
F-score
8/9
Altman Z
0.98
Beneish M
−2.58
Dividend safety
n/a

Insider Decisions trades per month

Total sells 5.35
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 2 3 3 1 2 1 1 5 3 3 4 3
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 1,840.00
Revenue 335.41
Net Income (17.16)
Free Cash Flow 55.67
Net Debt 130.84
Current Ratio 1.45
Debt/Equity (25.95) (negative: negative equity)
P/E ratio 0.00
Fwd P/E 54.50 (above 35: high)
P/S ratio 5.30
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 55.91% (at or above 15%: strong)
Next Y EPS Growth 6,785.72% (at or above 15%: strong)
Next Y revenue growth 32.91% (at or above 10%: strong)
Next 5Y EPS Growth —

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 61.01%
10-year low 10-year high
EV/Sales against its own 10 years 63.70%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 72 72 111 122
Receivables 39 40 51 58
Inventory 39 48 69 81
Other — — — —
156 168 240 275
2023 2024 2025 Q'26
Payables 12 2 3 9
ST’ Debt — 15 — 64
Other 20 1 5 5
95 100 110 190

Compound Annual Growth %

10y 5y 3y
Sales — 70.20% 38.33%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — (16.52%) (32.84%)

Revenue $m

Mar Jun Sep Dec Year
’26 83 92 — — —
’25 60 72 74 86 292
’24 41 48 54 60 203
’23 33 38 48 44 164
’22 22 25 30 33 110
’21 8 9 11 21 50
’20 2 2 9 7 20
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 10 8 — — —
’25 (10) 0 18 20 29
’24 (20) (10) (8) 2 (37)
’23 (26) (14) (15) 7 (47)
’22 (48) (21) (18) (16) (103)
’21 (24) (20) (23) (29) (96)
’20 (29) (24) (17) (11) (81)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 10 8 — — —
’25 (10) 0 18 20 28
’24 (20) (11) (8) 2 (38)
’23 (26) (15) (15) 7 (49)
’22 (48) (21) (18) (16) (103)
’21 (24) (20) (23) (29) (97)
’20 (29) (24) (17) (11) (81)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 0.01 (0.18) — — —
’25 (0.06) (0.01) 0.00 0.06 0.00
’24 (0.14) (0.10) (0.11) (0.03) (0.37)
’23 (0.12) (0.14) (0.09) (0.10) (0.45)
’22 (0.25) (0.19) (0.16) (0.10) (0.70)
’21 (0.30) (0.41) (0.39) (0.42) (1.55)
’20 (0.89) (0.63) (0.35) (0.41) (2.14)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.4
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — 15.01 6.81 1.42 1.77 1.14 0.97 1.69 3.14

Analyst estimates 2026–2028

Powerpack
High — — 27.98 18.88 7.24 7.94 3.10 3.07 3.87 10.08
People
People Employees — 55 90 202 180 294 355 377 394 435
Revenue/emp, $m 0.00 0.03 0.03 0.01 0.11 0.17 0.31 0.43 0.52 0.67
Income, $m
Income, $m Revenue 1 2 2 3 20 50 110 164 203 292
Gross margin, % 99.26 99.74 100.00 41.11 54.35 73.14 79.47 82.52 81.86 85.41
EBT (13) (27) (60) (126) (91) (123) (96) (64) (57) 1
EBT margin, % (1,228.74) (1,706.56) (2,479.57) (4,630.35) (446.54) (247.48) (87.15) (38.74) (28.12) 0.19
Net income (13) (27) (60) (126) (91) (123) (95) (62) (55) 1
Depreciation 0 0 1 2 2 3 14 15 16 16
Per share, $
Per share, $ Revenue 0.58 0.77 0.20 0.10 0.48 0.63 0.81 1.19 1.38 1.82
Earnings (7.17) (13.09) (4.99) (4.81) (2.14) (1.55) (0.70) (0.45) (0.37) 0.00
Cash flow (8.73) (12.16) (4.67) (4.00) (1.89) (1.21) (0.76) (0.34) (0.25) 0.18
Capex (0.02) (0.35) (0.13) (0.04) (0.01) (0.01) 0.00 (0.02) (0.01) 0.00
Free cash flow (8.75) (12.51) (4.80) (4.04) (1.90) (1.22) (0.76) (0.36) (0.26) 0.17
Book value 16.81 19.75 6.26 0.55 0.79 1.21 0.33 (0.05) (0.20) 0.09
Shares, m 2 2 12 26 43 79 136 138 147 160
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2,065.79
P/S 0.00 0.00 84.52 67.63 10.27 4.67 1.38 1.91 2.45 4.32
P/B 0.00 0.00 2.72 12.75 6.21 2.43 3.36 0.00 0.00 92.00
EV/Sales 0.00 0.00 51.19 62.39 8.13 4.44 1.98 2.64 3.24 4.73
EV/FCF (0.35) (0.35) (2.15) (1.61) (2.05) (2.28) (2.11) (8.79) (17.39) 49.43
Cash, $m
Cash, $m Operating cash flow (16) (25) (56) (104) (81) (96) (103) (47) (37) 29
Capex 0 (1) (2) (1) 0 (1) (1) (2) (1) (1)
Free cash flow (16) (25) (58) (105) (81) (97) (103) (49) (38) 28
Balance, $m
Balance, $m Working capital 31 39 108 60 124 64 113 61 67 131
Total debt — — 32 58 87 88 189 191 232 220
Net debt (32) (42) (81) (17) (47) (14) 67 118 160 109
Shareholders’ equity 31 40 75 14 34 95 45 (7) (30) 14
Returns, %
Returns, % ROA (33.64) (67.63) (72.81) (109.67) (67.98) (52.95) (29.18) (18.66) (16.99) 0.16
ROIC 0.00 0.00 0.00 0.00 0.00 (89.00) (45.78) (24.63) (16.07) 12.65
ROE 29.43 59.16 (683.66) (279.56) (378.20) (190.28) (134.83) (324.20) 301.32 (6.96)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Xeris Biopharma Holdings, Inc. vs peers in Drug Manufacturers Specialty & Generic (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
PBH Prestige Consumer Healthcare Inc. $2.3B 13.9× 10.3× +6.48% (above 0%: growing) −36.46% (below 0%: shrinking) −14.19% (below 0%: shrinking) 51.25% 19.77% Compare
SUPN Supernus Pharmaceuticals, Inc. $2.3B — (loss-making) 103× +32.40% (above 0%: growing) n/m −109.26% (below 0%: shrinking) 84.63% (26.46%) Compare
PRGO Perrigo Company plc $2.3B — (loss-making) — (loss-making) −3.17% (below 0%: shrinking) n/m +18.37% (above 0%: growing) 30.69% 2.31% Compare
ALVO Alvotech $2.1B — (loss-making) 8.9× +2,310.95% (above 0%: growing) −99.51% (below 0%: shrinking) −496.58% (below 0%: shrinking) 56.47% 9.14% Compare
BCRX BioCryst Pharmaceuticals, Inc. $2.1B — (loss-making) — (loss-making) +33.61% (above 0%: growing) +1,450.00% (above 0%: growing) +153.22% (above 0%: growing) 98.24% 45.12% Compare
XERS Xeris Biopharma Holdings, Inc. $1.8B — (loss-making) 54.5× +28.74% (above 0%: growing) n/m +8,403.09% (above 0%: growing) 86.41% 5.62%
ANIP ANI Pharmaceuticals, Inc. $1.7B 14.9× 14.5× +25.87% (above 0%: growing) +194.59% (above 0%: growing) −22.19% (below 0%: shrinking) 62.35% 15.21% Compare
PAHC Phibro Animal Health Corporation $1.5B 15.8× 11.1× +4.77% (above 0%: growing) +28.57% (above 0%: growing) −35.73% (below 0%: shrinking) 33.88% 12.14% Compare
ETON Eton Pharmaceuticals, Inc. $1.5B 107× 40.3× +98.59% (above 0%: growing) n/m −8.78% (below 0%: shrinking) 67.61% 34.04% Compare
Median of peers $2.1B 15.4× 12.8× +29.14% +28.57% −18.19% 59.41% 13.68%

All 86 Drug Manufacturers Specialty & Generic stocks →

Xeris Biopharma Holdings, Inc. (XERS) key facts

  • Strength: Xeris Biopharma Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $291.8 million, up 43.7% from fiscal 2024.
  • Xeris Biopharma Holdings, Inc. (XERS) is a Drug Manufacturers Specialty & Generic company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, XERS traded at $10.31, a market capitalization of $1.8 billion.
  • Return on equity was −6.96% and debt-to-equity -25.95.
  • Its Piotroski F-score is 8 out of 9 and its Altman Z-score is 0.98 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Xeris Biopharma Holdings, Inc. (XERS) Latest News

13 Aug

Impact 3 · transcript

7 Aug

Impact 3 · transcript
stockrow.com/XERS · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com