Amylyx Pharmaceuticals, Inc. (AMLX) vs Xeris Biopharma Holdings, Inc. (XERS)

Amylyx Pharmaceuticals, Inc. and Xeris Biopharma Holdings, Inc. are both Drug Manufacturers Specialty & Generic companies. Amylyx Pharmaceuticals, Inc. is the larger, with a market value of $3.5B against $2.4B — 1.5× the size. Xeris Biopharma Holdings, Inc. grew revenue faster over the last twelve months: 38.4% against −77.1%. Amylyx Pharmaceuticals, Inc. has the higher net margin (0.00% vs −1.76%) and the lower return on invested capital (0.00% vs 27.2%). Across the 17 metrics below, Xeris Biopharma Holdings, Inc. leads on 12 and Amylyx Pharmaceuticals, Inc. on 5.

Valuation

Metric AMLX XERS Drug Manufacturers Specialty & Generic median
P/E n/m n/m 20.45
P/S 37.29 7.45 2.11
P/B 13.62 56.23 1.69
Price to free cash flow n/m 37.73 15.98
EV/EBITDA n/m 54.16 12.21
EV/Sales 34.44 7.78 2.79
Earnings yield (4.88%) (0.26%) (15.61%)
Free cash flow yield (4.01%) 2.65% 0.00%

Profitability

Metric AMLX XERS Drug Manufacturers Specialty & Generic median
Gross margin (42.65%) 87.38% 53.51%
Operating margin 0.00% 12.70% 0.00%
Net margin 0.00% (1.76%) (2.31%)
Free cash flow margin 0.00% 20.00% 0.00%
Return on equity (74.73%) (27.11%) (0.80%)
Return on assets (66.25%) (1.64%) (1.67%)
Return on invested capital 0.00% 27.22% 0.00%

Growth

Metric AMLX XERS Drug Manufacturers Specialty & Generic median
Revenue growth (TTM) (77.06%) 38.37% 5.22%
EPS growth (last fiscal year) 65.46% 100.86% 42.91%
Revenue growth, 5-year CAGR — 70.20% 7.24%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AMLX XERS Drug Manufacturers Specialty & Generic median
Debt to equity 0.00 3.89 0.04
Current ratio 12.12 2.15 2.46
Net debt to EBITDA 2.00 2.67 1.01

Dividend

Metric AMLX XERS Drug Manufacturers Specialty & Generic median
Dividend yield — — 1.47%
Payout ratio — — 0.28

Size

Metric AMLX XERS Drug Manufacturers Specialty & Generic median
Market cap 3.47b 2.38b 300.78m

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