Amylyx Pharmaceuticals, Inc.

AMLX Healthcare Drug Manufacturers Specialty & Generic

Amylyx Pharmaceuticals, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $87.4 million, down 77.1% from fiscal 2023. In the quarter to June 2026, revenue fell 100.6%, EPS grew 15.2% and free cash flow fell 24.5%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

26.34 1.31 −4.74%
Market cap
$3.5B
P/E
0.0×
Fwd P/E
−9.2×
Dividend yield
—
F-score
3/9
Altman Z
−2.95
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.15
Total sells 10.14
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — 1 — — — — 1 — — — — —
Sell — 1 5 5 5 — — — 1 — 5 1
Insider Ownership 4.40%

Capital & Financial Ratios $m

Market Cap 3,470.00
Revenue 87.37
Net Income (152.09)
Free Cash Flow (130.72)
Net Debt (250.76)
Current Ratio 12.12 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (9.21) (negative: loss-making)
P/S ratio 33.52 (above 10: high)
P/B ratio 12.25 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth 2.20%
Next Y EPS Growth 24.34% (at or above 15%: strong)
Next Y revenue growth (61.29%) (below 0%: weak)
Next 5Y EPS Growth 49.92% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 95.28%
10-year low 10-year high
P/B against its own 10 years 90.97%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2018 0.42
0.42
2017 0.60
0.24
0.36
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 371 177 317 251
Receivables 40 0 0 —
Inventory 38 — — —
Other — — — —
465 189 324 256
2023 2024 2025 Q'26
Payables 22 3 4 6
ST’ Debt — — — —
Other — — — —
82 28 23 21

Compound Annual Growth %

10y 5y 3y
Sales — — 574.28%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 124.63% (3.59%)

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’24 89 (1) 0 (1) 87
’23 71 98 103 108 381
’22 — — 0 22 22
’21 — — 0 — 0
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (37) (31) — — —
’25 (40) (25) (30) (28) (123)
’24 0 (67) (42) (59) (168)
’23 (5) 9 (5) 14 12
’22 (41) (46) (43) (50) (180)
’21 (13) (13) (21) (28) (75)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (41) (31) — — —
’25 (40) (25) (30) (28) (123)
’24 (1) (67) (78) (59) (204)
’23 (5) 8 (6) 13 11
’22 (41) (48) (44) (50) (182)
’21 (13) (13) (21) (28) (75)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.37) (0.39) — — —
’25 (0.42) (0.46) (0.37) (0.30) (1.53)
’24 (1.75) (1.07) (1.07) (0.55) (4.43)
’23 0.02 0.31 0.30 0.07 0.70
’22 (0.93) (0.93) (0.92) (0.65) (3.39)
’21 (2.33) (3.41) (3.42) (4.19) (13.35)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — — — — 6.51 11.82 1.58 2.60

Analyst estimates 2026–2028

Powerpack
High — — — — — — 39.78 41.93 19.95 16.96
People
People Employees — — — — 110 205 262 384 123 136
Revenue/emp, $m — — — — 0.01 0.00 0.08 0.99 0.71 0.00
Income, $m
Income, $m Revenue — — — — 1 0 22 381 87 —
Gross margin, % — — — — 100.00 100.00 86.54 93.32 (42.65) —
EBT — — — — (42) (88) (198) 54 (302) (145)
EBT margin, % — — — — (6,504.62) (30,852.98) (888.89) 14.26 (345.81) 0.00
Net income — 0 — — (42) (88) (198) 49 (302) (145)
Depreciation — — — — 0 0 (2) (9) (9) (5)
Per share, $
Per share, $ Revenue — — — — 0.11 0.04 0.38 5.66 1.28 0.00
Earnings — — — — (6.96) (13.35) (3.39) 0.73 (4.43) (1.53)
Cash flow — — — — (6.04) (11.36) (3.07) 0.18 (2.46) (1.30)
Capex — — — — (0.02) (0.05) (0.04) (0.02) (0.53) 0.00
Free cash flow — — — — (6.06) (11.41) (3.12) 0.16 (2.99) (1.31)
Book value — — — — 0.88 13.39 5.82 6.45 2.42 3.23
Shares, m — — — — 6 7 58 67 68 95
Valuation, ×
Valuation, × P/E — — — — 0.00 0.00 0.00 20.51 0.00 —
P/S — — — — 0.00 0.00 0.00 2.64 2.95 —
P/B — — — — 0.00 0.00 6.18 2.32 1.56 —
EV/Sales — — — — 0.00 0.00 0.00 1.67 0.94 —
EV/FCF — — — — (0.32) (0.32) (9.64) 59.61 (0.40) —
Cash, $m
Cash, $m Operating cash flow — — — — (37) (75) (180) 12 (168) (123)
Capex — — — — 0 0 (3) (1) (36) 0
Free cash flow — — — — (37) (75) (182) 11 (204) (123)
Balance, $m
Balance, $m Working capital — — — — 6 88 336 383 161 301
Total debt — — — — 1 — — — — —
Net debt — — — — (11) (96) (347) (371) (177) (317)
Shareholders’ equity — — — — 5 88 341 433 165 305
Returns, %
Returns, % ROA — — — — (599.55) (146.90) (79.82) 10.84 (84.87) (55.00)
ROIC — — — — 0.00 0.00 0.00 39.07 0.00 0.00
ROE — — — — 0.00 80.71 (209.43) 12.73 (100.88) (61.59)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2024 · latest quarter Dec 2024

Charts ten years each

Amylyx Pharmaceuticals, Inc. vs peers in Drug Manufacturers Specialty & Generic (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
RGC Regencell Bioscience Holdings Limited $4.7B — (loss-making) — — — +57.15% (above 0%: growing) 0.00% — Compare
INDV Indivior Pharmaceuticals Inc. $4.0B 11.2× 11.8× +13.58% (above 0%: growing) +580.00% (above 0%: growing) +58.57% (above 0%: growing) 85.42% 46.36% Compare
AMLX Amylyx Pharmaceuticals, Inc. $3.5B — (loss-making) — (loss-making) −100.61% (below 0%: shrinking) n/m −24.50% (below 0%: shrinking) 100.00% 0.00%
LQDA Liquidia Corporation $3.1B 21.9× 18.5× +1,842.73% (above 0%: growing) n/m +270.23% (above 0%: growing) 93.27% 49.81% Compare
HCM HUTCHMED (China) Limited Sponsored ADR $2.4B — (loss-making) — +510.07% (above 0%: growing) +419.25% (above 0%: growing) +113.21% (above 0%: growing) 60.90% 0.00% Compare
PBH Prestige Consumer Healthcare Inc. $2.3B 13.9× 10.3× +6.48% (above 0%: growing) −36.46% (below 0%: shrinking) −14.19% (below 0%: shrinking) 51.25% 19.77% Compare
SUPN Supernus Pharmaceuticals, Inc. $2.3B — (loss-making) 103× +32.40% (above 0%: growing) n/m −109.26% (below 0%: shrinking) 84.63% (26.46%) Compare
PRGO Perrigo Company plc $2.3B — (loss-making) — (loss-making) −3.17% (below 0%: shrinking) n/m +18.37% (above 0%: growing) 30.69% 2.31% Compare
ALVO Alvotech $2.1B — (loss-making) 8.9× +2,310.95% (above 0%: growing) −99.51% (below 0%: shrinking) −496.58% (below 0%: shrinking) 56.47% 9.14% Compare
Median of peers $2.4B 13.9× 11.8× +32.40% +191.40% +37.76% 58.69% 9.14%

All 86 Drug Manufacturers Specialty & Generic stocks →

Amylyx Pharmaceuticals, Inc. (AMLX) key facts

  • Concern: Amylyx Pharmaceuticals, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $87.4 million, down 77.1% from fiscal 2023.
  • Concern: Amylyx Pharmaceuticals, Inc. reported a net loss of $144.7 million, or a loss of $1.53 per share, for fiscal 2025.
  • Amylyx Pharmaceuticals, Inc. (AMLX) is a Drug Manufacturers Specialty & Generic company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, AMLX traded at $26.34, a market capitalization of $3.5 billion.
  • Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 33.5× sales.
  • Return on equity was −61.6% and debt-to-equity 0.00.
  • Its Piotroski F-score is 3 out of 9 and its Altman Z-score is −2.95 (distress zone) for fiscal 2024.

Source: company filings (standardised) and stockrow calculations.

Amylyx Pharmaceuticals, Inc. (AMLX) Latest News

13 Aug

Impact 3 · transcript
stockrow.com/AMLX · Data as of Dec 31, 2024 · For information only; not investment advice. · © 2026 stockrow.com