Xeris Biopharma Holdings, Inc.

XERS Healthcare Drug Manufacturers Specialty & Generic

Xeris Biopharma Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $291.8 million, up 43.7% from fiscal 2024.

Revenue
+44.2%
EPS
+1,479.0%
Free cash flow
+93.2%
Total debt
−13.6%

Quarter to September 2026, against a year earlier

15.16 2.08 +15.90%
Market cap
$2.4B
P/E
0.0×
Fwd P/E
−143×
Dividend yield
—
F-score
8/9
Altman Z
0.98
Beneish M
−2.58
Dividend safety
n/a

Xeris Biopharma Holdings, Inc. (XERS) Gross margin

Alert me on Gross margin

Xeris Biopharma Holdings, Inc.'s gross margin over the twelve months to 30 September 2026 was 87.4%, up 2.0 percentage points from fiscal 2025 (85.4%). Over the past ten years it has ranged from 41.1% (fiscal 2019) to 100.0% (fiscal 2018); the current reading is higher than 70% of that period. That is above the Drug Manufacturers Specialty & Generic industry median of 53.5% and above the Healthcare sector median of 54.5%.

Gross margin, annual

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Annual newest first

Period Gross margin Change (points)
FY2025 85.4% 3.55
FY2024 81.9% (0.66)
FY2023 82.5% 3.05
FY2022 79.5% 6.33
FY2021 73.1% 18.79
FY2020 54.4% 13.24
FY2019 41.1% (58.89)
FY2018 100.0% 0.26
FY2017 99.7% 0.48
FY2016 99.3% —

Quarterly newest first

Period Gross margin Change (points)
Sep 2026 88.4% 2.00
Jun 2026 86.4% (0.87)
Mar 2026 87.3% 0.04
Dec 2025 87.2% 2.02
33 more quarters

Against its own ten years

Low 41.1% High 100.0%
Ten-year median 82.2%
Current reading's percentile 79

Gross margin against peers

Company Gross margin
BCRX BioCryst Pharmaceuticals, Inc. compare 97.9%
XERS Xeris Biopharma Holdings, Inc. 87.4%
TRLV Trulieve Cannabis Corp. compare 60.6%
PBH Prestige Consumer Healthcare Inc. compare 52.5%
HCM HUTCHMED (China) Limited Sponsored ADR compare 44.4%
ALVO Alvotech compare 42.7%
PRGO Perrigo Company plc compare 32.3%
AMLX Amylyx Pharmaceuticals, Inc. compare −42.7%
RGC Regencell Bioscience Holdings Limited compare —
Drug Manufacturers Specialty & Generic industry median 53.5%
Healthcare sector median 54.5%
Market median 46.0%

What Gross margin is

Gross Margin tells an investor how much of each sale a company keeps after paying the direct costs of making or buying what it sells.

Gross Profit ÷ Revenue

The full definition of Gross margin →

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