Xeris Biopharma Holdings, Inc.

XERS Healthcare Drug Manufacturers Specialty & Generic

Xeris Biopharma Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $291.8 million, up 43.7% from fiscal 2024.

Revenue
+44.2%
EPS
+1,479.0%
Free cash flow
+93.2%
Total debt
−13.6%

Quarter to September 2026, against a year earlier

15.16 2.08 +15.90%
Market cap
$2.4B
P/E
0.0×
Fwd P/E
−143×
Dividend yield
—
F-score
8/9
Altman Z
0.98
Beneish M
−2.58
Dividend safety
n/a

Xeris Biopharma Holdings, Inc. (XERS) Return on equity

Alert me on Return on equity

Xeris Biopharma Holdings, Inc.'s return on equity over the twelve months to 30 September 2026 was −27.1%, down 20.2 percentage points from fiscal 2025 (−6.96%). Over the past ten years it has ranged from −683.7% (fiscal 2018) to 301.3% (fiscal 2024); the current reading is higher than 70% of that period. That is below the Drug Manufacturers Specialty & Generic industry median of −0.80% and in line with the Healthcare sector median of −26.0%.

Return on equity, annual

Embed this chart

Annual newest first

Period Return on equity Change (points)
FY2025 −6.96% (308.28)
FY2024 301.3% 625.52
FY2023 −324.2% (189.37)
FY2022 −134.8% 55.45
FY2021 −190.3% 187.92
FY2020 −378.2% (98.64)
FY2019 −279.6% 404.10
FY2018 −683.7% (742.82)
FY2017 59.2% 29.73
FY2016 29.4% —

Against its own ten years

Low −683.7% High 301.3%
Ten-year median −162.6%
Current reading's percentile 70

Return on equity against peers

Company Return on equity
BCRX BioCryst Pharmaceuticals, Inc. compare 91.6%
PBH Prestige Consumer Healthcare Inc. compare 8.23%
HCM HUTCHMED (China) Limited Sponsored ADR compare 0.00%
RGC Regencell Bioscience Holdings Limited compare 0.00%
ALVO Alvotech compare 0.00%
XERS Xeris Biopharma Holdings, Inc. −27.1%
TRLV Trulieve Cannabis Corp. compare −45.5%
PRGO Perrigo Company plc compare −51.4%
AMLX Amylyx Pharmaceuticals, Inc. compare −74.7%
Drug Manufacturers Specialty & Generic industry median −0.80%
Healthcare sector median −26.0%
Market median 1.01%

What Return on equity is

ROE shows how much profit a company earns for its shareholders on the equity they have in the business.

Annual: Net Income Allotted to Shareholders ÷ Average Common Equity; TTM: Net Income Allotted to Shareholders ÷ Average Common Equity (latest quarter)

The full definition of Return on equity →

More on XERS