Xeris Biopharma Holdings, Inc.

XERS Healthcare Drug Manufacturers Specialty & Generic

Xeris Biopharma Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $291.8 million, up 43.7% from fiscal 2024.

Revenue
+44.2%
EPS
+1,479.0%
Free cash flow
+93.2%
Total debt
−13.6%

Quarter to September 2026, against a year earlier

15.16 2.08 +15.90%
Market cap
$2.4B
P/E
0.0×
Fwd P/E
−143×
Dividend yield
—
F-score
8/9
Altman Z
0.98
Beneish M
−2.58
Dividend safety
n/a

Xeris Biopharma Holdings, Inc. (XERS) Return on invested capital

Alert me on Return on invested capital

Xeris Biopharma Holdings, Inc.'s return on invested capital over the twelve months to 30 September 2026 was 27.2%, up 14.6 percentage points from fiscal 2025 (12.7%). Over the past ten years it has ranged from −89.0% (fiscal 2021) to 12.7% (fiscal 2025) — the current reading is the highest in ten years. That is above the Drug Manufacturers Specialty & Generic industry median of 0.00% and above the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 12.7% 28.72
FY2024 −16.1% 8.56
FY2023 −24.6% 21.15
FY2022 −45.8% 43.22
FY2021 −89.0% (89.00)
FY2020 0.00% 0.00
FY2019 0.00% 0.00
FY2018 0.00% 0.00
FY2017 0.00% 0.00
FY2016 0.00% —

Against its own ten years

Low −89.0% High 12.7%
Ten-year median 0.00%
Current reading's percentile 100

Return on invested capital against peers

Company Return on invested capital
XERS Xeris Biopharma Holdings, Inc. 27.2%
PBH Prestige Consumer Healthcare Inc. compare 4.56%
AMLX Amylyx Pharmaceuticals, Inc. compare 0.00%
HCM HUTCHMED (China) Limited Sponsored ADR compare 0.00%
RGC Regencell Bioscience Holdings Limited compare 0.00%
TRLV Trulieve Cannabis Corp. compare 0.00%
ALVO Alvotech compare 0.00%
PRGO Perrigo Company plc compare −19.0%
BCRX BioCryst Pharmaceuticals, Inc. compare −312.7%
Drug Manufacturers Specialty & Generic industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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