Protagonist Therapeutics, Inc.

PTGX Healthcare Biotechnology

Protagonist Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, down 89.4% from fiscal 2024.

Revenue
+3,749.2%
EPS
+549.1%
Free cash flow
+839.7%

Quarter to June 2026, against a year earlier

131.78 3.48 −2.57%
Market cap
$8.8B
P/E
111×
Fwd P/E
31.2×
Dividend yield
—
F-score
4/9
Altman Z
61.55
Beneish M
−7.18
Dividend safety
n/a

Protagonist Therapeutics, Inc. (PTGX) P/S ratio

Alert me on P/S ratio

As of 5 November 2026, Protagonist Therapeutics, Inc. (PTGX) trades at a P/S ratio of 31.7×. Over the past ten years it has ranged from 0.0× (December 2019) to 1,034× (February 2020); the current reading is higher than 69% of that period. That is above the Biotechnology industry median of 9.2× and above the Healthcare sector median of 3.5×.

P/S ratio, daily

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Annual newest first

Period P/S ratio Change
FY2025 121× 2,105.80%
FY2024 5.5× (81.28%)
FY2023 29.2× 151.46%
FY2022 11.6× (79.93%)
FY2021 57.9× 139.08%
FY2020 24.2× (96.93%)
FY2019 790× 16,137.01%
FY2018 4.9× —
FY2017 0.0× —

Quarterly newest first

Period P/S ratio Change
Jun 2026 28.7× (69.06%)
Mar 2026 92.6× (23.24%)
Dec 2025 121× 495.91%
Sep 2025 20.2× 20.67%
26 more quarters

Against its own ten years

Low 0.0× High 1,034×
Ten-year median 15.6×
Current reading's percentile 61

P/S ratio against peers

Company P/S ratio
CAI Caris Life Sciences,�Inc. compare 7.1×
MDGL Madrigal Pharmaceuticals, Inc. compare 8.2×
TGTX TG Therapeutics, Inc. compare 10.3×
TWST Twist Bioscience Corporation compare 17.6×
KRYS Krystal Biotech, Inc. compare 18.9×
PTGX Protagonist Therapeutics, Inc. 31.7×
IBRX ImmunityBio, Inc. compare 51.0×
CYTK Cytokinetics, Incorporated compare 64.4×
SYRE Spyre Therapeutics, Inc. compare 8,160×
Biotechnology industry median 9.2×
Healthcare sector median 3.5×
Market median 1.9×

What P/S ratio is

Price to Sales Ratio shows how much investors pay for each dollar of a company’s annual sales, whether or not it is profitable.

(Stock Price × Shares (Basic, Weighted) (latest quarter)) ÷ Revenue (TTM)

The full definition of P/S ratio →

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