Axsome Therapeutics, Inc.

AXSM Healthcare Biotechnology

Axsome Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $638.5 million, up 65.5% from fiscal 2024.

Revenue
+51.9%
EPS
+73.9%
Free cash flow
−1,078.3%
Total debt
+4.04%

Quarter to September 2026, against a year earlier

132.46 2.66 +2.05%
Market cap
$6.8B
P/E
0.0×
Fwd P/E
−49.2×
Dividend yield
—
F-score
5/9
Altman Z
6.91
Beneish M
−2.53
Dividend safety
n/a

Axsome Therapeutics, Inc. (AXSM) Return on assets

Alert me on Return on assets

Axsome Therapeutics, Inc.'s return on assets over the twelve months to 30 September 2026 was −21.0%, up 8.1 percentage points from fiscal 2025 (−29.1%). Over the past ten years it has ranged from −121.6% (fiscal 2018) to −29.1% (fiscal 2025) — the current reading is the highest in ten years. That is above the Biotechnology industry median of −45.6% and above the Healthcare sector median of −29.3%.

Return on assets, annual

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Annual newest first

Period Return on assets Change (points)
FY2025 −29.1% 20.55
FY2024 −49.7% 2.36
FY2023 −52.0% 37.25
FY2022 −89.3% 5.94
FY2021 −95.2% (44.61)
FY2020 −50.6% 7.34
FY2019 −57.9% 63.65
FY2018 −121.6% (43.12)
FY2017 −78.5% (16.14)
FY2016 −62.3% (15.24)

Against its own ten years

Low −121.6% High −29.1%
Ten-year median −57.9%
Current reading's percentile 100

Return on assets against peers

Company Return on assets
LGND Ligand Pharmaceuticals Incorporated compare 2.77%
ORKA Oruka Therapeutics, Inc. compare −17.8%
IONS Ionis Pharmaceuticals, Inc. compare −18.9%
AXSM Axsome Therapeutics, Inc. −21.0%
BLTE Belite Bio, Inc. Sponsored ADR compare −21.6%
PRAX Praxis Precision Medicines, Inc. compare −36.8%
RYTM Rhythm Pharmaceuticals, Inc. compare −41.8%
MIRM Mirum Pharmaceuticals, Inc. compare −99.8%
ABVX Abivax SA Sponsored ADR compare −137.7%
Biotechnology industry median −45.6%
Healthcare sector median −29.3%
Market median 0.00%

What Return on assets is

ROA tells an investor how much profit a company earns for shareholders from the assets it uses to run its business.

Annual: Net Income Allotted to Shareholders ÷ Average Assets; TTM: Net Income Allotted to Shareholders ÷ Average Assets (latest quarter)

The full definition of Return on assets →

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