stockrowProtagonist Therapeutics, Inc.
PTGX Healthcare Biotechnology
Protagonist Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, down 89.4% from fiscal 2024.
- Revenue
- +3,749.2%
- EPS
- +549.1%
- Free cash flow
- +839.7%
Quarter to June 2026, against a year earlier
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Protagonist Therapeutics, Inc. (PTGX) Net margin
Protagonist Therapeutics, Inc.'s net margin over the twelve months to 30 June 2026 was 29.4%, up 312.2 percentage points from fiscal 2025 (−282.8%). Over the past ten years it has ranged from −33,414.3% (fiscal 2019) to 63.3% (fiscal 2024); the current reading is higher than 36% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.
Net margin, annual
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Annual newest first
| Period | Net margin | Change (points) |
|---|---|---|
| FY2025 | −282.8% | (346.17) |
| FY2024 | 63.3% | 194.93 |
| FY2023 | −131.6% | 347.67 |
| FY2022 | −479.3% | (20.32) |
| FY2021 | −458.9% | (227.87) |
| FY2020 | −231.1% | 33,183.22 |
| FY2019 | −33,414.3% | (33,288.42) |
| FY2018 | −125.9% | 58.33 |
| FY2017 | −184.2% | (184.20) |
| FY2016 | 0.00% | 0.00 |
Quarterly newest first
| Period | Net margin | Change (points) |
|---|---|---|
| Jun 2026 | 76.3% | 69.57 |
| Mar 2026 | 6.71% | 603.51 |
| Dec 2025 | −596.8% | 238.07 |
| Sep 2025 | −834.9% | (207.91) |
| 40 more quarters | Free account |
Against its own ten years
Net margin against peers
| Company | Net margin |
|---|---|
| TGTX TG Therapeutics, Inc. compare | 55.2% |
| KRYS Krystal Biotech, Inc. compare | 47.9% |
| PTGX Protagonist Therapeutics, Inc. | 29.4% |
| CAI Caris Life Sciences,�Inc. compare | 9.16% |
| SYRE Spyre Therapeutics, Inc. compare | 0.00% |
| MDGL Madrigal Pharmaceuticals, Inc. compare | −10.9% |
| TWST Twist Bioscience Corporation compare | −31.7% |
| IBRX ImmunityBio, Inc. compare | −598.6% |
| CYTK Cytokinetics, Incorporated compare | −686.6% |
| Biotechnology industry median | 0.00% |
| Healthcare sector median | 0.00% |
| Market median | 1.06% |
What Net margin is
Net Profit Margin tells an investor how much of each unit of revenue ends up as profit for shareholders after all costs, interest and taxes.
Net Income Allotted to Shareholders ÷ Revenue
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- Revenue
- Net income
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- Free cash flow
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- Operating margin
- Free cash flow margin
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- P/S ratio
- P/B ratio
- Price to free cash flow
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