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Friday 6 November 2026 Export PTGX’s income statement to Excel — free account

Protagonist Therapeutics, Inc.

PTGX Healthcare Biotechnology

Protagonist Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, down 89.4% from fiscal 2024.

Revenue
+3,749.2%
EPS
+549.1%
Free cash flow
+839.7%

Quarter to June 2026, against a year earlier

131.78 3.48 −2.57%
Market cap
$8.8B
P/E
111×
Fwd P/E
31.2×
Dividend yield
—
F-score
4/9
Altman Z
61.55
Beneish M
−7.18
Dividend safety
n/a
Overview Business Profile Earnings & Analysis
Financials
Income Statement Balance Sheet Cash Flow Metrics & Ratios
Segments Valuation Filings

Protagonist Therapeutics, Inc. (PTGX) P/B ratio

Alert me on P/B ratio

As of 5 November 2026, Protagonist Therapeutics, Inc. (PTGX) trades at a P/B ratio of 10.6×. Over the past ten years it has ranged from 0.0× (September 2016) to 12.4× (August 2026); the current reading is higher than 97% of that period. That is above the Biotechnology industry median of 2.0× and above the Healthcare sector median of 2.3×.

P/B ratio, daily

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Annual newest first

Period P/B ratio Change
FY2025 9.0× 156.67%
FY2024 3.5× (10.87%)
FY2023 3.9× 61.04%
FY2022 2.5× (53.56%)
FY2021 5.3× 112.92%
FY2020 2.5× 8.63%
FY2019 2.3× 70.66%
FY2018 1.3× (56.88%)
FY2017 3.1× —

Quarterly newest first

Period P/B ratio Change
Jun 2026 9.6× (8.23%)
Mar 2026 10.5× 15.87%
Dec 2025 9.0× 37.62%
Sep 2025 6.6× 24.91%
26 more quarters

Against its own ten years

Low 0.0× High 12.4×
Ten-year median 3.6×
Current reading's percentile 96

P/B ratio against peers

Company P/B ratio
CYTK Cytokinetics, Incorporated compare n/m
IBRX ImmunityBio, Inc. compare n/m
KRYS Krystal Biotech, Inc. compare 6.2×
SYRE Spyre Therapeutics, Inc. compare 9.5×
PTGX Protagonist Therapeutics, Inc. 10.6×
CAI Caris Life Sciences,�Inc. compare 12.7×
TGTX TG Therapeutics, Inc. compare 13.6×
TWST Twist Bioscience Corporation compare 17.1×
MDGL Madrigal Pharmaceuticals, Inc. compare 18.7×
Biotechnology industry median 2.0×
Healthcare sector median 2.3×
Market median 1.7×

What P/B ratio is

Price to Book Value tells an investor how much the market pays for a company’s shares relative to the accounting net worth that belongs to common shareholders.

Stock Price ÷ (Common Equity (Total) (latest quarter) ÷ Shares (Basic, Weighted) (latest quarter))

The full definition of P/B ratio →

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