Friday 6 November 2026
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Guardant Health, Inc.
GH Healthcare Diagnostics & Research
Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024.
- Revenue
- +36.1%
- EPS
- −25.7%
- Free cash flow
- +18.7%
- Total debt
- +34.8%
Quarter to September 2026, against a year earlier
154.16
14.42
−8.55%
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Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Ten-year view | Analyst estimates Powerpack | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | TTM Sep ’26 | Trend | 10 yrs | 2026e | 2027e | 2028e | Next 3/yr |
| Income, $m | ||||||||||||||||||
| Income, $m | Revenue | 25 | 50 | 91 | 214 | 287 | 374 | 450 | 564 | 739 | 982 | 1,279 | +50.2% | 1,359 | 1,837 | 2,494 | +36.4% | |
| Gross margin, % | 12.38 | 36.56 | 52.33 | 67.01 | 67.73 | 67.11 | 65.23 | 59.74 | 60.79 | 64.46 | 65.19 | +52.1 pt | ||||||
| EBT | (46) | (83) | (84) | (70) | (246) | (384) | (653) | (479) | (435) | (418) | (486) | +27.7% | ||||||
| EBT margin, % | (182.71) | (166.96) | (92.92) | (32.52) | (85.76) | (102.89) | (145.36) | (84.90) | (58.87) | (42.52) | (37.99) | +140.2 pt | ||||||
| Net income | (46) | (83) | (84) | (68) | (246) | (385) | (655) | (479) | (436) | (416) | (485) | +27.7% | ||||||
| Per share, $ | ||||||||||||||||||
| Per share, $ | Revenue | 1.93 | 3.96 | 2.98 | 2.37 | 2.94 | 3.69 | 4.40 | 5.04 | 6.02 | 7.83 | 9.51 | +16.8% | |||||
| Earnings | (3.53) | (6.61) | (2.80) | (0.84) | (2.60) | (4.00) | (6.41) | (4.28) | (3.56) | (3.32) | (3.68) | (0.7%) | ||||||
| Cash flow | (2.81) | (5.74) | (2.37) | (0.52) | (1.07) | (2.06) | (3.03) | (2.90) | (1.95) | (1.47) | (1.29) | (6.9%) | ||||||
| Capex | (0.14) | (0.53) | (0.66) | (0.23) | (0.55) | (0.74) | (0.76) | (0.18) | (0.29) | (0.39) | (0.44) | +12.3% | ||||||
| Free cash flow | (2.95) | (6.27) | (3.04) | (0.75) | (1.62) | (2.80) | (3.79) | (3.08) | (2.24) | (1.86) | (1.73) | (5.0%) | ||||||
| Book value | 0.00 | 24.53 | 15.89 | 8.81 | 13.32 | 6.37 | 0.59 | 1.42 | (1.14) | (0.79) | (2.05) | n/m | ||||||
| Shares, m | 13 | 13 | 30 | 91 | 98 | 101 | 102 | 112 | 123 | 125 | 131 | +28.6% | ||||||
| Valuation, × | ||||||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0 | |||||
| P/S | 5.88 | 5.88 | 12.61 | 33.02 | 43.83 | 27.12 | 6.14 | 5.26 | 5.07 | 13.04 | 16.20 | 15.8 | ||||||
| P/B | 0.00 | 0.00 | 2.37 | 8.87 | 9.68 | 15.71 | 45.84 | 18.71 | 0.00 | 0.00 | 0.00 | 10.1 | ||||||
| EV/Sales | 1.94 | 1.94 | 7.99 | 30.77 | 40.38 | 27.66 | 6.42 | 5.21 | 5.48 | 13.35 | 16.55 | 14.1 | ||||||
| EV/FCF | (1.60) | (1.60) | (7.84) | (100.17) | (73.28) | (34.23) | (7.13) | (8.09) | (13.84) | (52.23) | (84.67) | (30.0) | ||||||
| Cash, $m | ||||||||||||||||||
| Cash, $m | Operating cash flow | (37) | (72) | (72) | (47) | (104) | (209) | (309) | (325) | (240) | (185) | (173) | +19.7% | |||||
| Capex | (2) | (7) | (20) | (21) | (54) | (75) | (77) | (20) | (35) | (48) | (59) | +44.4% | ||||||
| Free cash flow | (38) | (79) | (92) | (68) | (158) | (284) | (387) | (345) | (275) | (233) | (232) | +22.2% | ||||||
| Balance, $m | ||||||||||||||||||
| Balance, $m | Working capital | 89 | 223 | 422 | 525 | 1,822 | 919 | 998 | 1,141 | 830 | 1,163 | 970 | +33.1% | |||||
| Net debt | (78) | (221) | (412) | (483) | (989) | 202 | 126 | (29) | 303 | 302 | 1,502 | n/m | ||||||
| Shareholders’ equity | — | 309 | 483 | 798 | 1,298 | 645 | 60 | 159 | (140) | (99) | (276) | n/m | ||||||
| Returns, % | ||||||||||||||||||
| Returns, % | ROA | (26.90) | (51.90) | (18.29) | (9.76) | (15.69) | (18.13) | (34.32) | (28.23) | (26.67) | (23.79) | (30.68) | +3.1 pt | |||||
| ROIC | 0.00 | (54.57) | (81.60) | (16.31) | (51.42) | (30.32) | (182.59) | (271.47) | (170.17) | (134.56) | (25.68) | (134.6) pt | ||||||
| ROE | 31.71 | 61.09 | (58.31) | (11.81) | (24.21) | (41.75) | (185.65) | (438.13) | (4,584.50) | 348.42 | 153.90 | +316.7 pt | ||||||
| People | ||||||||||||||||||
| People | Employees | — | 348 | 454 | 622 | 864 | 1,373 | 1,793 | 1,779 | 2,021 | 2,506 | — | +28.0% | |||||
| Revenue/emp, $m | 0.00 | 0.14 | 0.20 | 0.34 | 0.33 | 0.27 | 0.25 | 0.32 | 0.37 | 0.39 | — | n/m | ||||||
Negative figures in brackets.
estimates
Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 5 Nov 2026
Business profile
Guardant Health, Inc. vs peers in Diagnostics & Research (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| MTD Mettler-Toledo International, Inc. | $33.6B | 37.6× | 36.1× | +4.48% (above 0%: growing) | +18.30% (above 0%: growing) | +33.01% (above 0%: growing) | 63.29% | 30.61% | Compare |
| ILMN Illumina, Inc. | $31.5B | 35.6× | 46.4× | +4.15% (above 0%: growing) | +48.98% (above 0%: growing) | +49.80% (above 0%: growing) | 73.52% | 27.02% | Compare |
| LH Labcorp Holdings Inc. | $29.5B | 29.5× | 26.7× | +6.92% (above 0%: growing) | +3.18% (above 0%: growing) | +44.73% (above 0%: growing) | 29.08% | 10.55% | Compare |
| DGX Quest Diagnostics Incorporated | $28.0B | 25.0× | 24.4× | +9.98% (above 0%: growing) | +29.36% (above 0%: growing) | +6.21% (above 0%: growing) | 33.65% | 15.47% | Compare |
| GH Guardant Health, Inc. | $20.6B | — (loss-making) | — (loss-making) | +36.12% (above 0%: growing) | n/m | +18.74% (above 0%: growing) | 65.42% | (36.78%) | |
| MEDP Medpace Holdings, Inc. | $17.8B | 34.6× | 35.8× | +8.50% (above 0%: growing) | +24.56% (above 0%: growing) | −16.59% (below 0%: shrinking) | 71.39% | 23.12% | Compare |
| RVTY Revvity Inc. | $16.8B | 71.9× | 66.2× | +4.29% (above 0%: growing) | +2.17% (above 0%: growing) | +26.97% (above 0%: growing) | 57.43% | 13.05% | Compare |
| ICLR ICON PLC | $15.1B | 34.5× | 34.6× | −2.86% (below 0%: shrinking) | n/m | −8.01% (below 0%: shrinking) | 24.29% | 9.82% | Compare |
| CRL Charles River Laboratories International, Inc. | $14.9B | 300× | 89.2× | −2.20% (below 0%: shrinking) | +530.30% (above 0%: growing) | +16.29% (above 0%: growing) | 36.42% | 20.62% | Compare |
| Median of peers | $22.9B | 35.1× | 36.0× | +4.39% | +24.56% | +21.63% | 46.93% | 18.05% |
Largest institutional holders 13F, quarter to 30 June 2026
Held by institutions
99.67%
Held by the ten largest
40.52%
| Holder | Shares | Stake | Change |
|---|---|---|---|
| Vanguard | 12.27m | 9.18% | −284.82k |
| BlackRock | 7.62m | 5.71% | −3.93m |
| T. Rowe Price | 6.53m | 4.89% | −1.25m |
| Fidelity (FMR) | 5.49m | 4.11% | +1.37m |
| Invesco | 4.43m | 3.32% | −516.71k |
| Goldman Sachs | 3.78m | 2.83% | −659.94k |
| Two Sigma | 3.72m | 2.78% | −510.23k |
| Franklin Templeton | 3.52m | 2.63% | +68.17k |
| Capital Group | 3.40m | 2.54% | −81.71k |
| Deep Track Capital, LP | 3.39m | 2.54% | +55.07k |
13F filings for the quarter to 30 June 2026: long positions in US-listed shares reported by managers with $100m or more, ~45 days after the quarter.
Pay and ownership Proxy statement filed 28 April 2026
Ownership
Directors and executive officers, together
5.60%
Blackrock Inc.
7.50%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more.
Read the proxy statement
Guardant Health, Inc. (GH) Latest News
6 Nov
5 Nov
29 Oct
20 Oct
17 Oct
15 Oct
14 Sep
GH metrics, ten years each
- Revenue
- Net income
- EPS (diluted)
- EBITDA
- Free cash flow
- Operating cash flow
- Gross margin
- Operating margin
- Net margin
- Free cash flow margin
- P/E ratio
- P/S ratio
- P/B ratio
- Price to free cash flow
- EV/EBITDA
- EV/Sales
- EV/FCF
- Return on equity
- Return on assets
- Return on invested capital
- Debt to equity
- Current ratio
- Total debt
- Shares outstanding
- Book value per share
- Revenue growth
- Piotroski F-score
- Altman Z-score
- Beneish M-score
Guardant Health is a precision oncology company that sells blood and tissue tests used in cancer care. Its tests help clinicians choose treatments, look for cancer remaining after treatment, monitor for recurrence and screen for cancer. The company also sells testing and data services to biopharmaceutical companies developing cancer therapies.
A liquid biopsy analyzes material in a blood sample rather than requiring a new tissue biopsy. Guardant360 Liquid and Guardant360 CDx help identify tumor mutations that can inform treatment for patients with advanced cancer. Guardant360 Tissue profiles tumor tissue. Guardant Reveal uses blood to detect residual or recurring disease in early-stage colorectal, breast and lung cancers; it is also offered for monitoring treatment response in advanced solid tumors.