Guardant Health, Inc.

GH Healthcare Diagnostics & Research

Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024.

Revenue
+36.1%
EPS
−25.7%
Free cash flow
+18.7%
Total debt
+34.8%

Quarter to September 2026, against a year earlier

154.16 14.42 −8.55%
Market cap
$20.6B
P/E
0.0×
Fwd P/E
−55.6×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.78
Dividend safety
n/a

Guardant Health, Inc. (GH) Operating margin

Alert me on Operating margin

Guardant Health, Inc.'s operating margin over the twelve months to 30 September 2026 was −39.4%, up 5.1 percentage points from fiscal 2025 (−44.5%). Over the past ten years it has ranged from −173.7% (fiscal 2016) to −38.4% (fiscal 2019); the current reading is higher than 90% of that period. That is below the Diagnostics & Research industry median of −5.68% and below the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −44.5% 15.49
FY2024 −60.0% 40.12
FY2023 −100.1% 20.96
FY2022 −121.1% (11.10)
FY2021 −110.0% (21.08)
FY2020 −88.9% (50.50)
FY2019 −38.4% 64.12
FY2018 −102.5% 51.17
FY2017 −153.7% 19.95
FY2016 −173.7% —

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 −36.8% 1.77
Jun 2026 −38.6% 1.68
Mar 2026 −40.2% 2.72
Dec 2025 −43.0% (5.62)
32 more quarters

Against its own ten years

Low −173.7% High −38.4%
Ten-year median −101.3%
Current reading's percentile 94

Operating margin against peers

Company Operating margin
MTD Mettler-Toledo International, Inc. compare 28.4%
MEDP Medpace Holdings, Inc. compare 21.4%
ILMN Illumina, Inc. compare 21.2%
DGX Quest Diagnostics Incorporated compare 14.6%
RVTY Revvity Inc. compare 12.7%
LH Labcorp Holdings Inc. compare 10.3%
ICLR ICON PLC compare 8.72%
CRL Charles River Laboratories International, Inc. compare 4.00%
GH Guardant Health, Inc. −39.4%
Diagnostics & Research industry median −5.68%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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