Guardant Health, Inc.

GH Healthcare Diagnostics & Research

Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024.

Revenue
+36.1%
EPS
−25.7%
Free cash flow
+18.7%
Total debt
+34.8%

Quarter to September 2026, against a year earlier

144.41 9.02 −5.88%
Market cap
$20.6B
P/E
0.0×
Fwd P/E
−55.6×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.78
Dividend safety
n/a

Guardant Health, Inc. (GH) Earnings & Analysis

Updated · Covers results through Q2 FY2026 · How this is made

Latest quarter

Guardant Health reported Q2 FY2026 revenue of $335.0 million, above the consensus of $316.0 million. Its adjusted loss per share was −$0.42, compared with the consensus estimate of −$0.40.

Revenue rose 44.3% from $232.1 million a year earlier. In its filing, Guardant attributed oncology revenue growth primarily to higher test volume. The company also said higher Shield test volume drove screening revenue growth, while milestones in companion diagnostic development and regulatory approval agreements lifted biopharma and data revenue.

Guardant reported a gross margin of 65.4%, compared with 65.0% a year earlier, and an operating margin of −38.5%, compared with −45.9%. The filing attributed higher sales and marketing expenses to commercial expansion and marketing for Shield and oncology. Diluted loss per share was −$0.90, compared with −$0.80 a year earlier. Free cash flow was −$69.5 million, compared with −$65.9 million.

Q2 FY2026 Q2 FY2025 Change
Revenue $335.0 million $232.1 million 44.3%
Diluted EPS −$0.90 −$0.80 —
Gross margin 65.4% 65.0% 0.4 percentage points
Operating margin −38.5% −45.9% 7.3 percentage points
Free cash flow −$69.5 million −$65.9 million —
Against the consensus Reported Consensus Result
Adjusted EPS −$0.42 −$0.40 Missed by 5.00%
Revenue $335.0 million $316.0 million Beat by 6.01%

Adjusted EPS is the figure the consensus estimates, not the GAAP EPS above.

What management said on the call

In its filing, Guardant said its revenue depends on payer coverage and reimbursement, and that payments can vary depending on whether it has a contract with a payer.

Guidance

For FY2026, Guardant raised its expected oncology volume growth to approximately 50.0% and oncology revenue growth to approximately 30.0%. The company also increased its outlook for non-GAAP operating expenses and now expects free cash flow burn of $195.0 million to $205.0 million, above its previous outlook.

Metric For Guide Previous guide Change
Free cash flow FY2026 $195.0 million–$205.0 million — New
Operating expenses, non-GAAP FY2026 $1.1 billion–$1.1 billion — New
Gross margin, non-GAAP FY2026 64.0%–65.0% — New
Units, Shield FY2026 270,000–285,000 — —
Revenue, Screening FY2026 $218.0 million–$230.0 million — New
Revenue, Biopharma and Data FY2026 Guardant Health expects FY2026 Biopharma & Data revenue growth in the low double-digit range. — —
Units growth, Oncology FY2026 50.0% — New
Revenue growth, Oncology FY2026 30.0% — New
Revenue FY2026 $1.3 billion–$1.4 billion — New