Guardant Health, Inc.

GH Healthcare Diagnostics & Research

Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024.

Revenue
+36.1%
EPS
−25.7%
Free cash flow
+18.7%
Total debt
+34.8%

Quarter to September 2026, against a year earlier

154.16 14.42 −8.55%
Market cap
$20.6B
P/E
0.0×
Fwd P/E
−55.6×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.78
Dividend safety
n/a

Guardant Health, Inc. (GH) Gross margin

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Guardant Health, Inc.'s gross margin over the twelve months to 30 September 2026 was 65.2%, up 0.7 percentage points from fiscal 2025 (64.5%). Over the past ten years it has ranged from 12.4% (fiscal 2016) to 67.7% (fiscal 2020); the current reading is higher than 60% of that period. That is above the Diagnostics & Research industry median of 48.3% and above the Healthcare sector median of 53.9%.

Gross margin, annual

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Annual newest first

Period Gross margin Change (points)
FY2025 64.5% 3.67
FY2024 60.8% 1.05
FY2023 59.7% (5.49)
FY2022 65.2% (1.88)
FY2021 67.1% (0.62)
FY2020 67.7% 0.72
FY2019 67.0% 14.68
FY2018 52.3% 15.77
FY2017 36.6% 24.18
FY2016 12.4% —

Quarterly newest first

Period Gross margin Change (points)
Sep 2026 65.4% 0.03
Jun 2026 65.4% 0.17
Mar 2026 65.2% 0.59
Dec 2025 64.6% (0.08)
32 more quarters

Against its own ten years

Low 12.4% High 67.7%
Ten-year median 62.6%
Current reading's percentile 58

Gross margin against peers

Company Gross margin
MEDP Medpace Holdings, Inc. compare 72.2%
ILMN Illumina, Inc. compare 67.9%
GH Guardant Health, Inc. 65.2%
MTD Mettler-Toledo International, Inc. compare 60.3%
RVTY Revvity Inc. compare 55.9%
CRL Charles River Laboratories International, Inc. compare 33.3%
DGX Quest Diagnostics Incorporated compare 33.1%
LH Labcorp Holdings Inc. compare 29.0%
ICLR ICON PLC compare 23.4%
Diagnostics & Research industry median 48.3%
Healthcare sector median 53.9%
Market median 45.1%

What Gross margin is

Gross Margin tells an investor how much of each sale a company keeps after paying the direct costs of making or buying what it sells.

Gross Profit ÷ Revenue

The full definition of Gross margin →

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