Guardant Health, Inc.

GH Healthcare Diagnostics & Research

Guardant Health, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $982.0 million, up 32.9% from fiscal 2024.

Revenue
+36.1%
EPS
−25.7%
Free cash flow
+18.7%
Total debt
+34.8%

Quarter to September 2026, against a year earlier

154.16 14.42 −8.55%
Market cap
$20.6B
P/E
0.0×
Fwd P/E
−55.6×
Dividend yield
—
F-score
5/9
Altman Z
2.02
Beneish M
−2.78
Dividend safety
n/a

Guardant Health, Inc. (GH) Net margin

Alert me on Net margin

Guardant Health, Inc.'s net margin over the twelve months to 30 September 2026 was −37.9%, up 4.5 percentage points from fiscal 2025 (−42.4%). Over the past ten years it has ranged from −182.7% (fiscal 2016) to −35.3% (fiscal 2019); the current reading is higher than 90% of that period. That is below the Diagnostics & Research industry median of −4.10% and below the Healthcare sector median of 0.00%.

Net margin, annual

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Annual newest first

Period Net margin Change (points)
FY2025 −42.4% 16.66
FY2024 −59.1% 25.97
FY2023 −85.0% 60.59
FY2022 −145.6% (37.04)
FY2021 −108.6% (20.06)
FY2020 −88.5% (53.22)
FY2019 −35.3% 58.56
FY2018 −93.9% 84.70
FY2017 −178.6% 4.19
FY2016 −182.7% —

Quarterly newest first

Period Net margin Change (points)
Sep 2026 −34.5% 1.42
Jun 2026 −35.9% 1.28
Mar 2026 −37.2% 8.53
Dec 2025 −45.7% (10.72)
32 more quarters

Against its own ten years

Low −182.7% High −35.3%
Ten-year median −91.2%
Current reading's percentile 94

Net margin against peers

Company Net margin
MTD Mettler-Toledo International, Inc. compare 21.9%
ILMN Illumina, Inc. compare 19.7%
MEDP Medpace Holdings, Inc. compare 18.2%
DGX Quest Diagnostics Incorporated compare 9.50%
RVTY Revvity Inc. compare 8.61%
LH Labcorp Holdings Inc. compare 6.88%
ICLR ICON PLC compare 5.45%
CRL Charles River Laboratories International, Inc. compare 1.01%
GH Guardant Health, Inc. −37.9%
Diagnostics & Research industry median −4.10%
Healthcare sector median 0.00%
Market median 1.06%

What Net margin is

Net Profit Margin tells an investor how much of each unit of revenue ends up as profit for shareholders after all costs, interest and taxes.

Net Income Allotted to Shareholders ÷ Revenue

The full definition of Net margin →

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