Illumina, Inc. ILMN

270.00 (3.90) (1.42%) as of 25 Sep
Market cap
$41.3B
P/E
50.4×
Indexes indicate stock being part of an index,
Growth Flags show if company had growth for consecutive years,
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 0.08
Total sells 592.86
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — 1 — — 1 — — — — — — —
Sell — — 2 — 2 — — 5 3 1 4 1
Insider Ownership 0.30%

Capital & Financial Ratios

Market Cap 41,250.00
Revenue 4,493.00
Net Income 824.00
Free Cash Flow 931.00
Net Debt 323.00
Current Ratio 1.80
Debt/Equity 0.53
P/E ratio 50.39
P/S ratio 9.16
P/B ratio 14.50
Past 5Y EPS Growth —
This Y EPS Growth 10.60%
Next Y EPS Growth 13.62%
Next 5Y EPS Growth 13.19%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 1,054 1,220 1,633 1,168
Receivables 734 735 854 764
Inventory 587 547 564 629
Other — — — —
2,609 2,746 3,289 2,834
2023 2024 2025 Q'26
Payables 245 221 240 230
ST’ Debt — — — —
Other — — — —
1,570 1,547 1,585 1,578
in millions of $

Compound Annual Growth

10y 5y 3y
Sales 6.94% 6.04% (1.78%)
Cash Flow 3.22% (0.02%) 40.15%
Earnings 6.29% 5.32% 0.00%
Book Value 3.95% (10.32%) (25.55%)

Revenue

Mar Jun Sep Dec Year
’26 1,091 1,159 — — —
’25 1,041 1,059 1,084 1,159 4,343
’24 1,076 1,112 1,080 1,104 4,372
’23 1,087 1,176 1,119 1,122 4,504
’22 1,223 1,162 1,115 1,084 4,584
’21 1,093 1,126 1,108 1,199 4,526
’20 859 633 794 953 3,239
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 289 201 — — —
’25 240 234 284 321 1,079
’24 77 80 316 364 837
’23 10 105 139 224 478
’22 172 125 (52) 147 392
’21 282 253 (272) 282 545
’20 281 240 153 406 1,080
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 251 161 — — —
’25 201 197 253 266 931
’24 41 49 284 335 709
’23 (43) 58 94 172 282
’22 111 54 (298) 59 (74)
’21 240 209 (324) 212 337
’20 241 201 105 344 891
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 0.87 1.35 — — —
’25 0.82 1.49 0.98 2.16 5.45
’24 (0.79) (12.48) 4.42 1.17 (7.69)
’23 0.02 (1.48) (4.77) (1.11) (7.34)
’22 0.55 (3.40) (24.26) (0.89) (28.00)
’21 1.00 1.26 2.08 0.71 5.04
’20 1.17 0.32 1.21 1.75 4.45
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

2.4
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
116.12 124.67 201.86 256.13 191.42 331.74 168.73 86.58 97.36 68.70

Analyst estimates 2026–2028

Powerpack
Low Price
183.12 224.44 362.46 370.39 393.19 540.63 416.34 232.05 156.66 153.06
High Price
5,500 6,200 7,300 7,700 7,850 9,150 10,260 9,300 9,030 8,650
Employees
0 0 0 0 0 0 0 0 0 1
Revenue/Emp
2,398 2,752 3,333 3,543 3,239 4,526 4,584 4,504 4,372 4,343
Revenue
69.47% 66.35% 69.01% 69.63% 68.01% 69.69% 64.83% 60.92% 65.44% 66.08%
Gross Margin
561 1,043 894 1,118 856 884 (4,336) (1,117) (1,179) 1,086
EBT
23.39% 37.90% 26.82% 31.56% 26.43% 19.53% (94.59%) (24.80%) (26.97%) 25.01%
EBT Margin
428 678 782 990 656 762 (4,404) (1,161) (1,223) 850
Net Income
171 186 220 234 227 283 394 432 354 270
Depreciation
16.31 18.85 22.67 24.10 22.03 30.17 29.20 28.51 27.50 28.02
Revenue/Sh
3.09 4.96 5.63 6.81 4.48 5.07 (28.00) (7.34) (7.69) 5.47
Earnings/Sh
5.30 5.99 7.77 7.15 7.35 3.63 2.50 3.03 5.26 6.96
Cash Flow/Sh
(1.84) (2.14) (2.01) (1.42) (1.29) (1.39) (2.97) (1.24) (0.80) (0.95)
Capex/Sh
3.46 3.86 5.76 5.73 6.06 2.25 (0.47) 1.78 4.46 6.01
Free CF/Sh
15.44 18.83 26.16 31.38 31.93 71.60 42.03 36.36 14.92 17.57
Book Value/Sh
147 146 147 147 147 150 157 158 159 155
Shares
40.50 43.59 51.91 47.39 80.34 72.71 0.00 0.00 0.00 23.93
PE Ratio
7.82 11.56 12.87 13.39 16.33 12.27 6.69 4.70 4.86 4.68
PS Ratio
8.26 11.57 11.15 10.28 11.27 5.17 4.65 3.68 8.95 7.47
PB Ratio
7.61 11.22 12.41 12.76 15.63 12.36 6.86 4.81 4.94 4.67
EV/Sales
35.95 55.91 49.67 54.53 57.65 172.65 (413.84) 77.12 30.55 22.13
EV/FCF
779 875 1,142 1,051 1,080 545 392 478 837 1,079
Op' Cash Flow
(271) (312) (296) (209) (189) (208) (466) (196) (128) (148)
Capex
508 563 846 842 891 337 (74) 282 709 931
FCF
1,613 2,234 2,686 3,786 3,239 1,620 788 1,039 1,199 1,704
Working Cap'
1,058 1,192 1,997 1,186 1,184 1,766 2,811 1,489 1,490 1,490
Total Debt
(501) (953) (1,515) (2,228) (2,288) 427 774 435 270 (143)
Net Debt
2,270 2,749 3,845 4,613 4,694 10,740 6,599 5,745 2,373 2,723
Sh' Equity
11.62% 15.22% 13.52% 14.04% 8.80% 6.68% (32.07%) (10.38%) (14.90%) 13.13%
ROA
20.74% 21.09% 23.69% 25.81% 15.07% (0.69%) (35.42%) (10.81%) (19.70%) 19.55%
ROIC
22.48% 28.93% 25.05% 23.69% 14.10% 9.87% (50.80%) (18.81%) (30.13%) 33.36%
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Illumina, Inc. peers in Diagnostics & Research

All 52 Diagnostics & Research stocks →

ILMN metrics, ten years each

Illumina, Inc. (ILMN) key facts

  • Illumina, Inc. (ILMN) is a Diagnostics & Research company in the Healthcare sector, listed on Nasdaq.
  • Illumina, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.3 billion, down 0.66% from fiscal 2024.
  • Net income was $850.0 million, or $5.47 per share (basic), a net margin of 19.6%.
  • As of September 25, 2026, ILMN traded at $270.00, a market capitalization of $41.3 billion.
  • At that price the stock trades at 50.4× trailing-twelve-month earnings and 9.2× sales.
  • Return on equity was 33.4% and debt-to-equity 0.53.

Source: company filings (standardised) and stockrow calculations.

Illumina, Inc. (ILMN) Latest News

News by impact score

Fine-tune

25 Sep

3

Illumina (ILMN) was removed from the Russell Small Cap Value Index, prompting potential mechanical selling and questions about current valuation. Momentum remains strong: 1-day +7.25%, 30-day +21.82%, YTD +103.87%, with 1-year TSR of 198.72% and 3-year TSR of 105.30% (5-year TSR down 28.62%). The stock trades around $273.90, while a fair value framework yields $199.63 (8.15% discount), signaling overvaluation by roughly 49%. Analysts expect 7% revenue growth over 3 years and margins rising from 18.3% to 20.6%. Risks include weaker research funding and Chinese regulatory uncertainty that could press earnings. The piece frames valuation volatility as a reset toward fair value and suggests stress-testing assumptions and exploring other stock ideas for diversification. Index removal can trigger short-term selling and alter valuation sentiment, affecting ILMN's near-term trajectory.

24 Sep

4

Illumina ILMN has surged ~95% YTD, outpacing the industry and the S&P 500. The rally stems from progress in core sequencing, expansion into multiomics, and broader services/data software, aided by post-GRAIL strategy. Q2 2026 revenue rose 9.5% to $1.16B; full-year 2026 guidance increased to $4.60-$4.64B and adjusted EPS to $5.30-$5.40, with margins around 23.4%-23.6%. NovaSeq X remains the growth engine, with 95+ systems placed in Q2 and most volumes on X. The balance sheet looks solid with about $1.17B cash and roughly $2.0B gross debt (long-term debt $1.49B; current $0.5B). Risks include tariffs, inflation, and China regulatory headwinds. 2026/27 consensus sees EPS of $5.36/$6.10 and revenues of $4.62B/$4.93B. Strategic expansion (multiomics and SomaLogic) and raised 2026 guidance suggest meaningful long-term growth potential.

20 Sep

3

ILMN shares rose 133% year to date. Further gains are projected based on ongoing company momentum and market positioning. Year-to-date stock gains and forward projections may lift near-term sentiment without altering core operations.

9 Sep

3

S&P Dow Jones Indices CEO comments on index restructuring that may affect Illumina's inclusion or weighting in key benchmarks. Index changes can trigger passive fund rebalancing and short-term trading flows for Illumina shares.

3

Illumina investors should mark September 21 for a key company event or announcement. Highlighting a specific future date for stock watchers indicates moderate potential influence on near-term sentiment and performance.

8 Sep

4

Illumina Inc. is among three stocks slated to join the S&P 500, triggering index-related buying from funds and heightened trading activity. S&P 500 inclusion drives passive inflows and lifts share demand for Illumina.

3

Multiomics market report shows spatial omics poised to outpace single-cell as next growth driver in genomics applications. Spatial omics expansion increases demand for Illumina sequencing platforms in core markets.

7 Sep

4

Illumina and Everpure will join the S&P 500 in the September rebalancing, triggering automatic purchases by index funds and ETFs and increasing demand for both stocks. S&P 500 inclusion drives substantial passive inflows and typically lifts share prices and visibility for the added company.

5 Sep

3

Illumina enters collaboration framework with Novacyt that may reshape its clinical sequencing strategies and market positioning. Novacyt framework targets core clinical sequencing operations with moderate trajectory effects.

28 Aug

3

Illumina is identified as the large-cap stock with competitive advantages while two others are flagged as risky. Positive assessment of Illumina competitive advantages may moderately influence its market perception.

5 Aug

3

Illumina (ILMN) shares rose amid strong clinical momentum in its sequencing and diagnostics operations. Clinical momentum supports incremental gains in revenue and market positioning without indicating transformative shifts.

3 Aug

3 transcript

Illumina held its Q2 2026 earnings call, covering quarterly financial results, operational updates, and forward guidance. Quarterly earnings calls deliver financial metrics and outlook that can shift near-term sentiment and valuation.

2 Aug

3

Illumina raised its 2026 revenue outlook on clinical sequencing growth, driving a 5.7% stock increase. Revenue outlook raise signals stronger clinical sequencing demand and lifts near-term valuation.

3

Illumina beat Q2 estimates and raised guidance but its stock could be 19% overvalued. Q2 beat and guidance raise create moderate short-term sentiment effects while overvaluation note caps trajectory changes.

31 Jul

4

Illumina lifts Q2 guidance on clinical strength, platform expansion and strategic focus. Raised guidance plus clinical and platform advances point to material trajectory shift for Illumina.

4

Illumina CEO highlights growth opportunities in genomic sequencing and AI integration to expand applications in healthcare and research. CEO comments on AI-driven sequencing opportunities indicate strategic moves that could significantly boost long-term trajectory and investor sentiment.

4 transcript

Illumina Inc (ILMN) posted Q2 2026 earnings with strong clinical growth driving revenue. Strong clinical growth in Q2 2026 earnings signals major positive revenue gains and shifts in market position.

3 transcript

Illumina reported Q2 results and outlook during its earnings call, covering revenue, margins, product pipeline progress and competitive positioning in sequencing markets. Quarterly earnings and guidance directly inform near-term financial expectations and investor sentiment for ILMN.

3 transcript

Illumina, Inc. held its Q2 2026 earnings call. Q2 earnings call delivers financial updates and outlook that can influence near-term stock movement and operations.

30 Jul

4 transcript

Illumina (ILMN) released its Q2 2026 earnings call transcript covering financial results, guidance, and operational updates. Earnings call transcript delivers key quarterly results and forward guidance that typically drive notable stock movement.

4

Eli Lilly joins Illumina's Billion Cell Atlas project to advance AI drug discovery. Partnership with Eli Lilly on large-scale cell atlas bolsters Illumina's genomics and AI drug discovery positioning.

3

Illumina reported Q2 earnings with analysis of key metrics on financial performance and operations. Q2 earnings release with metric breakdown moderately shapes near-term valuation and sentiment.

3

Illumina beat Q2 CY2026 sales expectations and issued a full-year outlook that slightly exceeds forecasts. Sales beat with modest outlook raise points to incremental positive financial momentum without altering long-term trajectory.

3

Illumina, Inc. (ILMN) reported financial results for the second quarter of fiscal year 2026. Quarterly earnings release supplies performance data that can shift near-term valuation and sentiment for Illumina.

29 Jul

3

Illumina's upcoming earnings will feature revenue from sequencing platforms and consumables, EPS figures, gross margin trends, and updated guidance amid ongoing competition in next-generation sequencing and potential demand shifts in research and clinical markets. Earnings previews highlight financial metrics and outlook that can drive short-term share price moves without altering long-term company trajectory.

28 Jul

3

Standard BioTools sells its mass cytometry business while Illumina buys out contingent payments to advance its merger with Treeline Biosciences. Illumina buyout of contingent payments advances merger with Treeline Biosciences.

20 Jul

4

Eli Lilly joins Illumina Atlas to map diseases with AI. Eli Lilly partnership strengthens Illumina's AI disease-mapping platform and strategic positioning.

16 Jul

4

Illumina faces German recall order over Element Sequencing patent ruling. German recall order over patent ruling directly threatens Illumina product sales and exposes company to further legal risks in major market.

3

Illumina expands its Billion Cell Atlas program with new AI drug developers. Program expansion with AI drug developers moderately strengthens Illumina's genomics and drug discovery positioning.

13 Jul

3

Jeff Bezos backed Grail before the company lost half its value, prompting debate over whether the investment was early or simply wrong. Grail value decline directly ties to Illumina's cancer detection strategy and market perception.

stockrow.com/ILMN · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com