Illumina, Inc.

ILMN Healthcare Diagnostics & Research

Illumina, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $4.3 billion, down 0.66% from fiscal 2024.

Revenue
+4.15%
EPS
+49.0%
Free cash flow
+49.8%
Total debt
+80.0%

Quarter to September 2026, against a year earlier

209.82 16.72 −7.38%
Market cap
$31.5B
P/E
35.6×
Fwd P/E
46.4×
Dividend yield
—
F-score
8/9
Altman Z
4.39
Beneish M
−2.51
Dividend safety
n/a

Revenue by products and services Fiscal 2025

  • Consumables
  • Service
  • Instruments

Every year since 2009 →

Insider Decisions last twelve months

Bought, $m 0.02
Sold, $m 659.42
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — 1 — — — — — — — — —
Sell 2 — 2 — — 5 3 1 4 1 — 1
Insider Ownership 0.21%

Capital & Financial Ratios $m

Size
Market Cap 31,450.00
Revenue ttm 4,538.00
Net income ttm 895.00
Free cash flow ttm 1,057.00
Net debt Q 452.00
Valuation
P/E 35.62 (above 35: high)
Forward P/E 46.40 (above 35: high)
Price / sales 6.98
Forward P/S Powerpack
Price / FCF 30.41
Price / book 10.07 (above 6: high)
Financial health
Current ratio Q 2.63 (at or above 1.5: strong)
Debt / equity Q 0.57
Interest coverage Q 12.71
Growth
Revenue growth Q +4.15% (above 0%: growing)
Operating income growth Q +34.36% (above 0%: growing)
EPS, this year +11.89%
EPS, next year A +13.77%
Revenue, next year A +6.56%
EPS, past 5 yrs +4.14%
EPS, next 5 yrs A +13.59%

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/E against its own 10 years 18.07%
10-year low 10-year high
P/S against its own 10 years 34.18%
10-year low 10-year high
P/B against its own 10 years 53.91%
10-year low 10-year high
EV/Sales against its own 10 years 35.72%
10-year low 10-year high
EV/FCF against its own 10 years 16.69%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 1,054 1,220 1,633 1,337
Receivables 734 735 854 738
Inventory 587 547 564 667
Other — — — —
2,609 2,746 3,289 3,035
2023 2024 2025 Q'26
Payables 245 221 240 241
ST’ Debt — — — —
Other — — — —
1,570 1,547 1,585 1,156

Compound Annual Growth %

10y 5y 3y
Sales 6.94% 6.04% (1.78%)
Cash Flow 3.22% (0.02%) 40.15%
Earnings 6.29% 5.32% 0.00%
Book Value 3.95% (10.32%) (25.55%)

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 0.87 1.35 1.43 — —
’25 0.82 1.49 0.98 2.16 5.45
’24 (0.79) (12.48) 4.42 1.17 (7.69)
’23 0.02 (1.48) (4.77) (1.11) (7.34)
’22 0.55 (3.40) (24.26) (0.89) (28.00)
’21 1.00 1.26 2.08 0.71 5.04
’20 1.17 0.32 1.21 1.75 4.45
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 1,091 1,159 1,129 — —
’25 1,041 1,059 1,084 1,159 4,343
’24 1,076 1,112 1,080 1,104 4,372
’23 1,087 1,176 1,119 1,122 4,504
’22 1,223 1,162 1,115 1,084 4,584
’21 1,093 1,126 1,108 1,199 4,526
’20 859 633 794 953 3,239
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 289 201 419 — —
’25 240 234 284 321 1,079
’24 77 80 316 364 837
’23 10 105 139 224 478
’22 172 125 (52) 147 392
’21 282 253 (272) 282 545
’20 281 240 153 406 1,080
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 251 161 379 — —
’25 201 197 253 266 931
’24 41 49 284 335 709
’23 (43) 58 94 172 282
’22 111 54 (298) 59 (74)
’21 240 209 (324) 212 337
’20 241 201 105 344 891
Fiscal quarters ending in the months shown.

Valuation

The price implies free cash flow after share-based pay growing 15.4% a year for ten years. It grew 1.3% a year over the last ten.

Implied
15.4%
10 years, reported
1.3%
Open the model

Target Price Range

Analyst price targets

Recommendation Rating

2.5
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue 2,398 2,752 3,333 3,543 3,239 4,526 4,584 4,504 4,372 4,343 4,538 +6.8% 4,628 4,929 5,286 +6.8%
Gross margin, % 69.47 66.35 69.01 69.63 68.01 69.69 64.83 60.92 65.44 66.08 67.87 (3.4) pt
EBT 561 1,043 894 1,118 856 884 (4,336) (1,117) (1,179) 1,086 1,059 +7.6%
EBT margin, % 23.39 37.90 26.82 31.56 26.43 19.53 (94.59) (24.80) (26.97) 25.01 23.34 +1.6 pt
Net income 428 678 782 990 656 762 (4,404) (1,161) (1,223) 850 895 +7.9%
Per share, $
Per share, $ Revenue 16.31 18.85 22.67 24.10 22.03 30.17 29.20 28.51 27.50 28.02 30.05 +6.2%
Earnings 3.09 4.96 5.63 6.81 4.48 5.07 (28.00) (7.34) (7.69) 5.47 5.89 +6.6%
Cash flow 5.30 5.99 7.77 7.15 7.35 3.63 2.50 3.03 5.26 6.96 8.15 +3.1%
Capex (1.84) (2.14) (2.01) (1.42) (1.29) (1.39) (2.97) (1.24) (0.80) (0.95) (1.15) (7.0%)
Free cash flow 3.46 3.86 5.76 5.73 6.06 2.25 (0.47) 1.78 4.46 6.01 7.00 +6.3%
Book value 15.44 18.83 26.16 31.38 31.93 71.60 42.03 36.36 14.92 17.57 20.83 +1.4%
Shares, m 147 146 147 147 147 150 157 158 159 155 153 +0.6%
Valuation, ×
Valuation, × P/E 40.87 43.99 52.40 47.83 81.09 73.39 0.00 0.00 0.00 23.93 35.62 36.4
P/S 7.89 11.67 12.99 13.51 16.49 12.38 6.76 4.74 4.86 4.68 6.98 9.6
P/B 8.34 11.68 11.26 10.38 11.38 5.22 4.69 3.72 8.95 7.47 10.07 8.3
EV/Sales 7.68 11.32 12.53 12.89 15.78 12.57 6.74 4.94 5.03 4.76 7.19 9.4
EV/FCF 36.29 56.45 50.15 55.07 58.22 175.54 (406.62) 79.25 31.12 22.57 31.31 15.8
Cash, $m
Cash, $m Operating cash flow 779 875 1,142 1,051 1,080 545 392 478 837 1,079 1,230 +3.7%
Capex (271) (312) (296) (209) (189) (208) (466) (196) (128) (148) (173) (6.5%)
Free cash flow 508 563 846 842 891 337 (74) 282 709 931 1,057 +7.0%
Balance, $m
Balance, $m Working capital 1,613 2,234 2,686 3,786 3,239 1,620 788 1,039 1,199 1,704 1,879 +0.6%
Net debt (501) (953) (1,515) (2,228) (2,288) 356 (550) 435 270 (143) 452 (13.0%)
Shareholders’ equity 2,270 2,749 3,845 4,613 4,694 10,740 6,599 5,745 2,373 2,723 3,145 +2.0%
Returns, %
Returns, % ROA 11.62 15.22 13.52 14.04 8.80 6.68 (32.07) (10.38) (14.90) 13.13 13.78 +1.5 pt
ROIC 20.74 21.09 23.69 25.81 15.07 (0.69) (43.18) (10.81) (19.70) 19.55 16.70 (1.2) pt
ROE 22.48 28.93 25.05 23.69 14.10 9.87 (50.80) (18.81) (30.13) 33.36 32.39 +10.9 pt
People
People Employees 5,500 6,200 7,300 7,700 7,850 9,150 10,260 9,300 9,030 8,650 — +5.2%
Revenue/emp, $m 0.44 0.44 0.46 0.46 0.41 0.49 0.45 0.48 0.48 0.50 — +1.6%
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 5 Nov 2026

Business profile

Updated

Illumina makes tools for reading and analyzing genetic information. Its sequencing systems determine the order of the chemical building blocks in DNA, while its arrays test samples for known genetic markers. Customers use these tools in research, drug development and clinical testing. Illumina was founded in 1998, is headquartered in San Diego and is led by chief executive Jacob Thaysen.

Its products include instruments, the materials needed to prepare and run samples, and software that helps customers manage and interpret the resulting data. The systems range from smaller machines used for targeted analyses to production-scale instruments used for whole-genome sequencing. Illumina also provides sequencing and genotyping services and support for customers that own its equipment.

Where the money comes from and where it goes Fiscal 2025

Fiscal 2025: revenue by products and services, and margins
Consumables 3,227 74.30%
Service 634 14.60%
Instruments 482 11.10%
Gross margin 66.08%
Operating margin 18.58%
Pre-tax margin 25.01%

Revenue by segment since 2009

Illumina, Inc. vs peers in Diagnostics & Research (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
IDXX IDEXX Laboratories, Inc. $52.8B 44.8× 37.3× +9.86% (above 0%: growing) +17.30% (above 0%: growing) +17.58% (above 0%: growing) 62.94% 33.14% Compare
A Agilent Technologies, Inc. $48.4B 33.8× 34.1× +8.06% (above 0%: growing) +8.47% (above 0%: growing) +69.50% (above 0%: growing) 55.48% 23.64% Compare
WAT Waters Corporation $44.5B 194× 81.0× +120.91% (above 0%: growing) −67.02% (below 0%: shrinking) −66.71% (below 0%: shrinking) 50.25% 7.24% Compare
IQV IQVIA Holdings Inc. $43.7B 31.8× 34.8× +8.00% (above 0%: growing) +10.16% (above 0%: growing) −21.25% (below 0%: shrinking) 33.83% 12.92% Compare
MTD Mettler-Toledo International, Inc. $33.6B 37.6× 36.1× +4.48% (above 0%: growing) +18.30% (above 0%: growing) +33.01% (above 0%: growing) 63.29% 30.61% Compare
ILMN Illumina, Inc. $31.5B 35.6× 46.4× +4.15% (above 0%: growing) +48.98% (above 0%: growing) +49.80% (above 0%: growing) 73.52% 27.02%
LH Labcorp Holdings Inc. $29.5B 29.5× 26.7× +6.92% (above 0%: growing) +3.18% (above 0%: growing) +44.73% (above 0%: growing) 29.08% 10.55% Compare
DGX Quest Diagnostics Incorporated $28.0B 25.0× 24.4× +9.98% (above 0%: growing) +29.36% (above 0%: growing) +6.21% (above 0%: growing) 33.65% 15.47% Compare
GH Guardant Health, Inc. $20.6B — (loss-making) — (loss-making) +36.12% (above 0%: growing) n/m +18.74% (above 0%: growing) 65.42% (36.78%) Compare
Median of peers $38.6B 33.8× 34.8× +8.96% +10.16% +18.16% 52.87% 14.20%

All 49 Diagnostics & Research stocks →

From the latest earnings call

Updated

  • CEO Jacob Thaysen said clinical customers were expanding instrument capacity, while CFO Ankur Dhingra said clinical sequencing-consumables revenue grew 15% excluding China in Q2.
  • Thaysen said Illumina was sharing some higher memory and freight costs with customers and using operational measures to offset the increases.

Largest institutional holders 13F, quarter to 30 June 2026

Held by institutions 102.49%
Held by the ten largest 52.65%
Holder Shares Stake Change
BlackRock 19.19m 12.71% +167.81k
Capital Group 15.65m 10.37% −122.39k
Vanguard 14.64m 9.70% −168.63k
State Street 6.51m 4.31% +77.94k
WCM INVESTMENT MANAGEMENT, LLC 6.21m 4.11% +283.53k
Fidelity (FMR) 4.52m 3.00% +2.98m
PRIMECAP Management 3.51m 2.33% +1.45m
AQR Capital Management 3.48m 2.30% −443.68k
Geode Capital Management 2.95m 1.95% −104.61k
Corvex Management LP 2.83m 1.87% −999.06k
13F filings for the quarter to 30 June 2026: long positions in US-listed shares reported by managers with $100m or more, ~45 days after the quarter.

Pay and ownership Proxy statement filed 9 April 2026

Ownership

Directors and executive officers, together 2.90%
Capital World Investors 13.30%
BlackRock, Inc. 11.90%
The Vanguard Group 10.50%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Illumina, Inc. (ILMN) Latest News

2 Nov

1 Nov

Impact 3 · · Simply Wall St.

31 Oct

ILMN metrics, ten years each

stockrow.com/ILMN · Data as of Nov 5, 2026 · For information only; not investment advice. · © 2026 stockrow.com