Septerna, Inc.

SEPN Healthcare Biotechnology

Septerna, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, up 4,174.5% from fiscal 2024.

Revenue
+22,375.6%
EPS
+48.2%
Free cash flow
−9.01%

Quarter to June 2026, against a year earlier

49.54 2.19 +4.63%
Market cap
$2.2B
P/E
0.0×
Fwd P/E
−32.6×
Dividend yield
—
F-score
5/9
Altman Z
3.41
Beneish M
32.85
Dividend safety
n/a

Septerna, Inc. (SEPN) Return on assets

Alert me on Return on assets

Septerna, Inc.'s return on assets over the twelve months to 30 June 2026 was −4.94%, up 4.4 percentage points from fiscal 2025 (−9.29%). That is above the Biotechnology industry median of −45.6% and above the Healthcare sector median of −29.3%.

Return on assets, annual

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Annual newest first

Period Return on assets Change (points)
FY2025 −9.29% 15.16
FY2024 −24.5% (24.45)
FY2023 0.00% —

Return on assets against peers

Company Return on assets
AUPH Aurinia Pharmaceuticals Inc compare 46.5%
VCEL Vericel Corporation compare 6.86%
LKFT Lakefront Biotherapeutics - Sponsored ADR compare 0.00%
SEPN Septerna, Inc. −4.94%
ZYME Zymeworks Inc. compare −37.3%
PVLA Palvella Therapeutics, Inc. compare −37.7%
IMNM Immunome, Inc. compare −59.0%
VERA Vera Therapeutics, Inc. compare −72.3%
BHVN Biohaven Ltd. compare −161.3%
Biotechnology industry median −45.6%
Healthcare sector median −29.3%
Market median 0.00%

What Return on assets is

ROA tells an investor how much profit a company earns for shareholders from the assets it uses to run its business.

Annual: Net Income Allotted to Shareholders ÷ Average Assets; TTM: Net Income Allotted to Shareholders ÷ Average Assets (latest quarter)

The full definition of Return on assets →

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