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Friday 6 November 2026 Export SEPN’s income statement to Excel — free account

Septerna, Inc.

SEPN Healthcare Biotechnology

Septerna, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, up 4,174.5% from fiscal 2024.

Revenue
+22,375.6%
EPS
+48.2%
Free cash flow
−9.01%

Quarter to June 2026, against a year earlier

48.95 1.60 +3.38%
Market cap
$2.2B
P/E
0.0×
Fwd P/E
−32.6×
Dividend yield
—
F-score
5/9
Altman Z
3.41
Beneish M
32.85
Dividend safety
n/a
Overview
Financials
Income Statement Balance Sheet Cash Flow Metrics & Ratios

Septerna, Inc. (SEPN) EV/FCF

Alert me on EV/FCF

As of 5 November 2026, Septerna, Inc. (SEPN) trades at a EV/FCF of 15.2×. Over the past ten years it has ranged from −5.7× (September 2025) to 15.3× (August 2026); the current reading is higher than 100% of that period.

EV/FCF, daily

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Annual newest first

Period EV/FCF Change
FY2025 6.9× 160.32%
FY2024 2.7× 19.96%
FY2023 2.2× —

Quarterly newest first

Period EV/FCF Change
Jun 2026 9.7× 58.45%
Mar 2026 6.1× (11.62%)
Dec 2025 6.9× 121.79%
Sep 2025 3.1× —
7 more quarters

Against its own ten years

Low −5.7× High 15.3×
Ten-year median 5.7×
Current reading's percentile 100

EV/FCF against peers

Company EV/FCF
PVLA Palvella Therapeutics, Inc. compare −62.4×
ZYME Zymeworks Inc. compare −15.1×
IMNM Immunome, Inc. compare −7.0×
VERA Vera Therapeutics, Inc. compare −5.2×
BHVN Biohaven Ltd. compare −4.5×
LKFT Lakefront Biotherapeutics - Sponsored ADR compare 0.6×
AUPH Aurinia Pharmaceuticals Inc compare 9.7×
SEPN Septerna, Inc. 15.2×
VCEL Vericel Corporation compare 42.8×

What EV/FCF is

EV/Free CF shows how the value of a whole company, debt included, compares with the free cash its business produces.

((Stock Price × Shares (Basic, Weighted) (latest quarter)) + (Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter)) − Cash & Short Term Investments (latest quarter)) ÷ (Operating Cash Flow (TTM) + Property, Plant, Equipment Change (Net) (TTM) + Intangible Assets Change (Net) (TTM))

The full definition of EV/FCF →

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