Palvella Therapeutics, Inc. (PVLA) vs Septerna, Inc. (SEPN)

Palvella Therapeutics, Inc. and Septerna, Inc. are both Biotechnology companies. Palvella Therapeutics, Inc. and Septerna, Inc. are of similar size ($1.8B and $1.8B). Septerna, Inc. grew revenue faster over the last twelve months: 13,520.1% against 146.7%. Palvella Therapeutics, Inc. has the higher net margin (0.00% vs −24.5%) and the higher return on invested capital (0.00% vs −189.0%). Across the 15 metrics below, Septerna, Inc. leads on 10 and Palvella Therapeutics, Inc. on 5.

Valuation

Metric PVLA SEPN Biotechnology median
P/E n/m n/m 8.50
P/S 41.55 16.42 9.71
P/B 7.96 4.20 2.13
Price to free cash flow n/m 13.81 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 35.55 12.66 9.21
Earnings yield (4.01%) (1.50%) (33.15%)
Free cash flow yield (1.86%) 7.24% (25.50%)

Profitability

Metric PVLA SEPN Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin 0.00% (44.04%) 0.00%
Net margin 0.00% (24.51%) 0.00%
Free cash flow margin 0.00% 118.93% 0.00%
Return on equity (46.63%) (6.34%) (56.36%)
Return on assets (37.70%) (4.94%) (48.04%)
Return on invested capital 0.00% (189.01%) 0.00%

Growth

Metric PVLA SEPN Biotechnology median
Revenue growth (TTM) 146.67% 13,520.11% 6.02%
EPS growth (last fiscal year) 52.62% 84.85% 30.26%
Revenue growth, 5-year CAGR 8.03% — 9.41%
Net income growth, 5-year CAGR 0.00% — 0.00%

Health

Metric PVLA SEPN Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 21.18 4.99 4.72
Net debt to EBITDA 1.50 5.86 0.96

Dividend

Metric PVLA SEPN Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric PVLA SEPN Biotechnology median
Market cap 1.83b 1.75b 135.18m

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